公开(公告)号：US20250000924A1

公开(公告)日：2025-01-02

申请号：US18748930

申请日：2024-06-20

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Myung Suk KIM ,  Wook Bin LEE ,  Hye Jin KO ,  Le Thi TAM ,  Tae Kyeom KANG ,  Gun PARK

IPC: A61K36/13 ,  A61K45/06 ,  A61P37/08

Abstract: The present invention relates to a composition for the prevention, improvement/amelioration or treatment of allergic disease containing an extract of Taxus cuspidata as an active ingredient, and more specifically, to a composition for the prevention, improvement/amelioration or treatment of allergic respiratory disease comprising an ethanol extract of Taxus cuspidata or a fraction thereof as an active ingredient. In the present invention, the effectiveness of Taxus cuspidata extract in treating allergic respiratory disease was confirmed in an animal model of allergic asthma, and the anti-allergic efficacy of compounds isolated from Taxus cuspidata ethanol extract was confirmed. Therefore, Taxus cuspidata extract of the present invention can be useful as a composition for the prevention, amelioration or treatment of allergic respiratory diseases, particularly allergic asthma or allergic bronchitis.

公开(公告)号：US20240216458A1

公开(公告)日：2024-07-04

申请号：US18540186

申请日：2023-12-14

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Myung Suk KIM ,  Sang Hoon JUNG ,  Wook Bin LEE ,  Tam Thi LE ,  Tae Kyeom KANG

IPC: A61K36/482 ,  A61K31/05 ,  A61K31/085 ,  A61K31/122 ,  A61K31/192 ,  A61K31/216 ,  A61K31/353 ,  A61K31/7048 ,  A61P37/08

CPC classification number: A61K36/482 ,  A61K31/05 ,  A61K31/085 ,  A61K31/122 ,  A61K31/192 ,  A61K31/216 ,  A61K31/353 ,  A61K31/7048 ,  A61P37/08 ,  A61K2236/333

Abstract: The present invention relates to a composition for the prevention, improvement or treatment of allergic diseases containing a Cassia mimosoides L. extract as an active ingredient, and more specifically, to a composition for the prevention, improvement or treatment of allergic diseases containing an ethanol extract of Cassia mimosoides L. as an active ingredient. In the present invention, the effect of Cassia mimosoides L. extract in treating allergic respiratory diseases was confirmed in an animal model of allergic asthma, and the anti-allergic effect of the compounds isolated from an ethanol extract of Cassia mimosoides L. was confirmed. Therefore, Cassia mimosoides L. extract of the present invention can be useful as a composition for preventing, improving, or treating allergic respiratory diseases, particularly allergic asthma or allergic bronchitis.