公开(公告)号：US20250000924A1

公开(公告)日：2025-01-02

申请号：US18748930

申请日：2024-06-20

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Myung Suk KIM ,  Wook Bin LEE ,  Hye Jin KO ,  Le Thi TAM ,  Tae Kyeom KANG ,  Gun PARK

IPC: A61K36/13 ,  A61K45/06 ,  A61P37/08

Abstract: The present invention relates to a composition for the prevention, improvement/amelioration or treatment of allergic disease containing an extract of Taxus cuspidata as an active ingredient, and more specifically, to a composition for the prevention, improvement/amelioration or treatment of allergic respiratory disease comprising an ethanol extract of Taxus cuspidata or a fraction thereof as an active ingredient. In the present invention, the effectiveness of Taxus cuspidata extract in treating allergic respiratory disease was confirmed in an animal model of allergic asthma, and the anti-allergic efficacy of compounds isolated from Taxus cuspidata ethanol extract was confirmed. Therefore, Taxus cuspidata extract of the present invention can be useful as a composition for the prevention, amelioration or treatment of allergic respiratory diseases, particularly allergic asthma or allergic bronchitis.