公开(公告)号：US09980954B2

公开(公告)日：2018-05-29

申请号：US15403404

申请日：2017-01-11

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Hyunah Choo ,  Sun-Joon Min ,  Yun Kyung Kim ,  Hoon Ryu ,  Hyemyung Seo ,  Juhyeon Kim ,  Jihoon Jang ,  Sungsu Lim ,  Younghee Kim ,  Yu Jin Hwang ,  Yong Seo Cho

IPC: A61K31/47 ,  A61K31/4709 ,  A61K31/5377

CPC classification number: A61K31/47 ,  A61K31/4709 ,  A61K31/5377

Abstract: The present disclosure relates to a quinoline derivative which inhibits the activity of histone methyltransferases (ESET/SETDB1) specific for the histone molecule H3K9 or a pharmaceutically acceptable salt thereof and a use thereof.