公开(公告)号：US09682942B2

公开(公告)日：2017-06-20

申请号：US14784147

申请日：2014-05-30

Applicant: KOWA COMPANY, LTD.

Inventor： Koichi Yamazaki ,  Kennosuke Matsuda ,  Taichi Kusakabe ,  Tadaaki Ohgiya ,  Kimiyuki Shibuya

IPC: A01N43/54 ,  A61K31/505 ,  C07D239/47

CPC classification number: C07D239/47 ,  C07B2200/13

Abstract: It is an object of the present invention to provide a novel form of (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid, which is useful for preventing and/or treating diseases such as dyslipidemia.(S)-trans-{4-[({2-[({1-[3,5-bis(Trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid hydrochloride.