公开(公告)号：US09045777B2

公开(公告)日：2015-06-02

申请号：US14029465

申请日：2013-09-17

申请人： Korea Center for Disease Control and Prevention ,  Chungbuk National University Industry-Academic Cooperation Foundation

发明人： Young Ki Choi ,  Chun Kang ,  Kee Jong Hong ,  Min Suk Song ,  Yun Hee Baek

IPC分类号： C12N15/85 ,  C12N7/00 ,  C12N9/12

CPC分类号： C12N15/85 ,  C12N7/00 ,  C12N9/1252 ,  C12N2760/16051 ,  C12N2760/16052 ,  C12N2760/16151 ,  C12N2760/16152 ,  C12N2830/85 ,  C12Y207/07007

摘要： The present invention relates to a pol I promoter derived from Vero cells and a recombinant vector containing the same. When the pol I promoter derived from Vero cells according to the present invention is utilized, viruses can be manufactured efficiently, and consequently, the manufacture of both seasonal influenza vaccine and pandemic vaccine can be prepared more quickly to usefully address either situation.

摘要翻译： 本发明涉及由Vero细胞衍生的pol I启动子和含有该载体的重组载体。 当利用衍生自根据本发明的Vero细胞的pol I启动子时，可以有效地制造病毒，因此可以更快地制备季节性流感疫苗和大流行性流感疫苗的制造以有效地解决任一情况。

公开(公告)号：US20140011260A1

公开(公告)日：2014-01-09

申请号：US14029465

申请日：2013-09-17

申请人： Chungbuk National University Industry-Academic Cooperation Foundation ,  Korea Center for Disease Control and Prevention

发明人： Young Ki Choi ,  Chun Kang ,  Kee Jong Hong ,  Min Suk Song ,  Yun Hee Baek

IPC分类号： C12N15/85 ,  C12N7/00

CPC分类号： C12N15/85 ,  C12N7/00 ,  C12N9/1252 ,  C12N2760/16051 ,  C12N2760/16052 ,  C12N2760/16151 ,  C12N2760/16152 ,  C12N2830/85 ,  C12Y207/07007

摘要： The present invention relates to a pol I promoter derived from Vero cells and a recombinant vector containing the same. When the pol I promoter derived from Vero cells according to the present invention is utilized, viruses can be manufactured efficiently, and consequently, the manufacture of both seasonal influenza vaccine and pandemic vaccine can be prepared more quickly to usefully address either situation.

摘要翻译： 本发明涉及由Vero细胞衍生的pol I启动子和含有该载体的重组载体。 当利用衍生自根据本发明的Vero细胞的pol I启动子时，可以有效地制造病毒，因此可以更快地制备季节性流感疫苗和大流行性流感疫苗的制造以有效地解决任一情况。