公开(公告)号：US11007134B1

公开(公告)日：2021-05-18

申请号：US16835930

申请日：2020-03-31

Applicant: L'OREAL

Inventor： Laurianne Le Claire ,  Miao Wang ,  Jerome Cottard

IPC: A61K8/68 ,  A61K8/11 ,  A61K8/90 ,  A61K8/85 ,  A61K8/35 ,  A61Q19/00 ,  A61K8/55

Abstract: The ceramide composition includes capsules dispersed in the ceramide composition, the capsules comprising a shell and a core. The shell includes a polycaprolactone, a block copolymer, and a surfactant. The core includes ceramide NP, hydroxypalmitoyl sphinganine, 2-oleamido-1,3-octadecanediol, and a hydrophobic solvent. The core has a weight ratio of the ceramide NP of (i) and the hydroxypalmitoyl sphinganine of (ii) to the 2-oleamido-1,3-octadecanediol of (iii) is from 1:2.5 to 1:5. Additionally, the ceramide composition includes hydroxyacetophenone and hydrophilic solvent.