公开(公告)号：US20140348967A1

公开(公告)日：2014-11-27

申请号：US14371057

申请日：2013-01-14

Applicant: LABORATORIES EXPANSCIENCE

Inventor： Philippe Msika ,  Jacques Legrand ,  Sebastien Garnier

IPC: C11B1/06 ,  A61K36/54

CPC classification number: C11B1/06 ,  A23D9/007 ,  A23D9/02 ,  A23L2/52 ,  A23L19/07 ,  A23L33/105 ,  A23L33/11 ,  A23L33/115 ,  A61K8/922 ,  A61K36/54 ,  A61Q19/06 ,  A61Q19/08 ,  C11B1/08

Abstract: The present invention relates to the use of avocado seeds in order to obtain avocado oil enriched in alkyl polyols and/or acetylated derivatives thereof, said avocado seeds accounting for 10 to 50% by weight relative to the total weight of avocado used. The invention also relates to a method for obtaining avocado oil enriched in alkyl polyols or acetylated derivatives thereof from at least avocado seeds, said avocado seeds accounting for 10 to 50% by weight relative to the total weight of avocado used. The invention also relates to avocado oil enriched in alkyl polyols and/or acetylated derivatives thereof, obtainable by the present method. The invention also relates to the use of avocado oil in order to prepare an avocado oil concentrate enriched in alkyl polyols and/or acetylated derivatives thereof, or to prepare an avocado unsaponifiable enriched in alkyl polyols. Lastly, the invention relates to an avocado unsaponifiable enriched in alkyl polyols or an avocado oil concentrate enriched in alkyl polyols and/or acetylated derivatives thereof, obtainable from said avocado oil, for use as a drug, advantageously in the prevention and/or treatment of conjunctive tissue disorders such as arthrosis, articular pathologies such as rheumatism, or periodontal diseases such as gingivitis or periodontitis.

Abstract translation: 本发明涉及鳄梨种子的使用以获得富含烷基多元醇和/或其乙酰化衍生物的鳄梨油，所述鳄梨种子占所用鳄梨总重量的10至50重量％。 本发明还涉及从至少鳄梨种子获得富含烷基多元醇或其乙酰化衍生物的鳄梨油的方法，所述鳄梨种子占所用鳄梨总重量的10至50重量％。 本发明还涉及通过本方法获得的富含烷基多元醇和/或其乙酰化衍生物的鳄梨油。 本发明还涉及鳄梨油的用途，以制备富含烷基多元醇和/或其乙酰化衍生物的鳄梨油浓缩物，或制备不可皂化的富含烷基多元醇的鳄梨油。 最后，本发明涉及一种不可皂化的富含鳄梨油的富含烷基多元醇的牛油果油或富含其烷基多元醇和/或其乙酰化衍生物的鳄梨油浓缩物，其可从所述鳄梨油获得，有利地用于预防和/或治疗 结膜组织疾病如关节病，关节病变如风湿病，或牙周病如牙龈炎或牙周炎。