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    SYSTEMS AND METHODS FOR RUN-TIME SEQUENCING RUN QUALITY MONITORING
    1.
    发明申请
    SYSTEMS AND METHODS FOR RUN-TIME SEQUENCING RUN QUALITY MONITORING 有权

    公开(公告)号：US20220072681A1

    公开(公告)日：2022-03-10

    申请号：US17478096

    申请日：2021-09-17

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Yerramalli Subramaniam ,  Puneet Suri ,  Sylvia Chang ,  Chengyong Yang

    IPC: B24B41/06 ,  G16B30/00 ,  G05B11/01 ,  B24B5/04

    Abstract: Systems and methods of providing run-time quality control and monitoring of a single or multiple sequencing runs are provided herein. In some embodiments, the run-time system includes or is in communication with a processor capable of determining various types of run-time information relating to the quality, progress, etc. of various sequencing runs. In some embodiments, the system can also be in communication with a user interface, for example, a GUI, capable of representing and communicating various types of information to a user regarding the quality of the individual or multiple runs, the functioning of the instrument, an error event, etc. Additionally, the system can capable of receiving actionable information from a user via the GUI thereby allowing the user to terminate or repeat various sequencing steps in a particular run, terminate a entire run, terminate all runs, allow a run to proceed, etc.

    SYSTEMS AND METHODS FOR RUN-TIME SEQUENCING RUN QUALITY MONITORING
    5.
    发明申请
    SYSTEMS AND METHODS FOR RUN-TIME SEQUENCING RUN QUALITY MONITORING 有权

    公开(公告)号：US20240391053A1

    公开(公告)日：2024-11-28

    申请号：US18672549

    申请日：2024-05-23

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Yerramalli Subramaniam ,  Chengyong Yang ,  Sylvia Chang ,  Puneet Suri

    IPC: B24B41/06 ,  B24B5/04 ,  G05B11/01 ,  G16B30/00

    Abstract: Systems and methods of providing run-time quality control and monitoring of a single or multiple sequencing runs are provided herein. In some embodiments, the run-time system includes or is in communication with a processor capable of determining various types of run-time information relating to the quality, progress, etc. of various sequencing runs. In some embodiments, the system can also be in communication with a user interface, for example, a GUI, capable of representing and communicating various types of information to a user regarding the quality of the individual or multiple runs, the functioning of the instrument, an error event, etc. Additionally, the system can capable of receiving actionable information from a user via the GUI thereby allowing the user to terminate or repeat various sequencing steps in a particular run, terminate a entire run, terminate all runs, allow a run to proceed, etc.

    Systems and methods for run-time sequencing run quality monitoring
    6.
    发明授权
    Systems and methods for run-time sequencing run quality monitoring 有权

    公开(公告)号：US11135699B2

    公开(公告)日：2021-10-05

    申请号：US15652425

    申请日：2017-07-18

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Yerramalli Subramaniam ,  Puneet Suri ,  Sylvia Chang ,  Chengyong Yang

    IPC: B24B41/06 ,  G16B30/00 ,  G05B11/01 ,  B24B5/04

    Abstract: Systems and methods of providing run-time quality control and monitoring of a single or multiple sequencing runs are provided herein. In some embodiments, the run-time system includes or is in communication with a processor capable of determining various types of run-time information relating to the quality, progress, etc. of various sequencing runs. In some embodiments, the system can also be in communication with a user interface, for example, a GUI, capable of representing and communicating various types of information to a user regarding the quality of the individual or multiple runs, the functioning of the instrument, an error event, etc. Additionally, the system can capable of receiving actionable information from a user via the GUI thereby allowing the user to terminate or repeat various sequencing steps in a particular run, terminate a entire run, terminate all runs, allow a run to proceed, etc.

    Methods and Systems for Variant Detection
    7.
    发明申请
    Methods and Systems for Variant Detection 审中-公开
    变异检测方法与系统

    公开(公告)号：US20160313280A1

    公开(公告)日：2016-10-27

    申请号：US15130532

    申请日：2016-04-15

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： David A. Denny ,  David Woo ,  Manjula Aliminati ,  Siva Kumar Samsani ,  Stephanie J. Schneider ,  Yoke Peng Lim ,  Sylvia Chang

    IPC: G01N27/447

    CPC classification number: G01N27/44717 ,  G06F19/22

    Abstract: In one exemplary embodiment, a method for detecting variants in electropherogram data is provided. The method includes receiving electropherogram data from an instrument and analyzing the electropherogram data to identify mixed bases in the electropherogram data. The method further includes identifying features within the electropherogram data indicative of errors and validating the identified mixed bases. Then the method includes determining variants in the electropherogram data based on the validated mixed bases.

    Abstract translation: 在一个示例性实施例中，提供了一种用于检测电泳图数据中的变体的方法。 该方法包括从仪器接收电泳图数据，并分析电泳图数据以识别电泳图数据中的混合碱基。 该方法还包括识别电泳图中指示错误并验证所识别的混合碱基的特征。 然后该方法包括基于经验证的混合碱基来确定电泳图数据中的变体。

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