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公开(公告)号:US20180186777A1
公开(公告)日:2018-07-05
申请号:US15757103
申请日:2016-09-03
申请人: LUPIN LIMITED
发明人: Vidya RAMDAS , Rajeshkumar Maganlal LORIYA , Moloy BANERJEE , Pradeep Rangrao PATIL , Advait Arun JOSHI , Laxmikant Shamlal DATRANGE , Deepak Sahebrao WALKE , Talha Hussain KHAN , Amit Kumar DAS , Ganesh Navinchandra GOTE , Vaibhav Madhukar KALHAPURE , Venkata P. PALLE , Rajender Kumar KAMBOJ
IPC分类号: C07D405/12 , C07D405/14 , C07D413/14 , C07D417/14 , A61P29/00
CPC分类号: C07D405/12 , A61P29/00 , C07D405/14 , C07D413/14 , C07D417/14
摘要: The present invention relates to sulfonamide compounds Formula (I) wherein the substituents are as described herein, and their use in a medicine for the treatment of diseases, disorders associated with the inhibition of Voltage-gated sodium channels (VGSC) particularly NaV1.7. It further relates to the compounds herein and their pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof useful in treating diseases, disorders, syndromes and/or conditions associated with the inhibition of Voltage-gated sodium channels (VGSC) particularly NaV1.7. The invention also relates to process for the preparation of the compounds of the invention.
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公开(公告)号:US20170137415A1
公开(公告)日:2017-05-18
申请号:US15300337
申请日:2015-03-27
申请人: LUPIN LIMITED
发明人: Vidya RAMDAS , Rajeshkumar Maganlal LORIYA , Deepak Sahebrao WALKE , Amit Kumar DAS , Talha Hussain KHAN , Moloy BANERJEE , Venkata P. PALLE , Rajender Kumar KAMBOJ
IPC分类号: C07D417/12 , C07D417/14
CPC分类号: C07D417/12 , C07D417/14
摘要: The present invention relates to the compound of Formula (I) wherein the substituents are as described herein, and their use in a medicine for the treatment of diseases, disorders associated with the inhibition of Voltage-gated sodium channels (VGSC) particularly NaV1.7. It further relates to the compounds herein and their pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof useful in treating diseases, disorders, syndromes and/or conditions associated with the inhibition of Voltage-gated sodium channels (VGSC) particularly NaV1.7. The invention also relates to process for the preparation of the compounds of the invention.
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