公开(公告)号：US20190099447A1

公开(公告)日：2019-04-04

申请号：US16207871

申请日：2018-12-03

申请人： MEMORIAL SLOAN-KETTERING CANCER CENTER

发明人： Jae H. Park ,  Isabelle Riviere ,  Xiuyan Wang ,  Terence Purdon ,  Michel Sadelain ,  Renier J. Brentjens

IPC分类号： A61K35/17 ,  A61P35/02 ,  C07K16/28

摘要： Provided are methods and compositions for providing early cell therapy options to subjects, offering the potential benefit of avoiding higher risk treatment modalities.

公开(公告)号：US20240042031A1

公开(公告)日：2024-02-08

申请号：US18476870

申请日：2023-09-28

申请人： MEMORIAL SLOAN-KETTERING CANCER CENTER

发明人： Christopher S. Hackett ,  Renier J. Brentjens ,  Jedd D. Wolchok ,  Paul B. Chapman ,  Sarwish Rafiq ,  Terence Purdon

IPC分类号： A61K39/00 ,  C07K16/30 ,  C07K14/725 ,  C07K14/705 ,  C07K14/54 ,  A61P35/00 ,  C12N5/0783

CPC分类号： A61K39/4632 ,  C07K16/3084 ,  C07K14/7051 ,  C07K14/70521 ,  C07K14/70578 ,  C07K14/70575 ,  C07K14/54 ,  A61P35/00 ,  A61K39/4611 ,  C12N5/0636 ,  C07K2317/622 ,  C07K2317/24 ,  C07K2319/02 ,  C07K2319/03

摘要： The presently disclosed subject matter provides for antigen-recognizing receptors that specifically target GD3 and cells comprising such GD3-targeted antigen-recognizing receptors. The presently disclosed subject matter further provides uses of the GD3-targeted antigen-recognizing receptors for treatment.