公开(公告)号：US20230021837A1

公开(公告)日：2023-01-26

申请号：US17779900

申请日：2020-11-25

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Anu MATHEW ,  Mingyue WANG ,  Christopher CAMPBELL ,  Katarzyna HAYNESWORTH ,  Nikhil PADMANABHAN ,  Martin STENGELIN ,  Paridhi GUPTA ,  Rashmi SRIRAM

IPC: G01N33/564 ,  G01N33/543

Abstract: The invention relates to assay methods and kits for assessing autoimmune diseases in a human subject. In embodiments, the present disclosure provides assay methods and kits for diagnosing a subject with or predicting that a subject will develop Type 1 diabetes. In embodiments, the present disclosure provides assay methods and kits for assessing responsiveness of a subject having Type 1 diabetes to treatment with alefacept. In embodiments, the present disclosure provides assay methods and kits for diagnosing a subject with systemic lupus erythematosus. In embodiments, the present disclosure provides assay methods and kits for determining if a subject is at risk of a systemic lupus erythematosus flare. In embodiments, the present disclosure provides assay methods and kits for diagnosing a subject with celiac disease.