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公开(公告)号:US20230021837A1
公开(公告)日:2023-01-26
申请号:US17779900
申请日:2020-11-25
发明人: Anu MATHEW , Mingyue WANG , Christopher CAMPBELL , Katarzyna HAYNESWORTH , Nikhil PADMANABHAN , Martin STENGELIN , Paridhi GUPTA , Rashmi SRIRAM
IPC分类号: G01N33/564 , G01N33/543
摘要: The invention relates to assay methods and kits for assessing autoimmune diseases in a human subject. In embodiments, the present disclosure provides assay methods and kits for diagnosing a subject with or predicting that a subject will develop Type 1 diabetes. In embodiments, the present disclosure provides assay methods and kits for assessing responsiveness of a subject having Type 1 diabetes to treatment with alefacept. In embodiments, the present disclosure provides assay methods and kits for diagnosing a subject with systemic lupus erythematosus. In embodiments, the present disclosure provides assay methods and kits for determining if a subject is at risk of a systemic lupus erythematosus flare. In embodiments, the present disclosure provides assay methods and kits for diagnosing a subject with celiac disease.
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公开(公告)号:US20220003766A1
公开(公告)日:2022-01-06
申请号:US17246360
申请日:2021-04-30
发明人: Jacob N. WOHLSTADTER , George SIGAL , Anu MATHEW , Anastasia AKSYUK , David ROUTENBERG , Martin STENGELIN , John KENTEN , Timothy J. BREAK , Seth B. HARKINS , Michael TSIONSKY
IPC分类号: G01N33/569 , C12Q1/70
摘要: The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.
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公开(公告)号:US20210190778A1
公开(公告)日:2021-06-24
申请号:US17132380
申请日:2020-12-23
发明人: Anahit AGHVANYAN , Eli N. GLEZER , John KENTEN , George SIGAL , Martin STENGELIN
IPC分类号: G01N33/543 , G01N33/569 , G01N33/53 , G01N33/533 , C12Q1/6804 , G01N21/66 , G01N21/76 , G01N21/77 , G01N33/58
摘要: The present invention is directed to methods for improving assay specificity and performance in binding assays.
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公开(公告)号:US20220357318A1
公开(公告)日:2022-11-10
申请号:US17813965
申请日:2022-07-21
发明人: Anahit AGHVANYAN , Eli N. GLEZER , John KENTEN , George SIGAL , Martin STENGELIN , David ROUTENBERG
IPC分类号: G01N33/543 , C12Q1/6832 , C12Q1/6837 , C12Q1/6844
摘要: The present invention is directed to methods for improving assay specificity and performance in binding assays.
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公开(公告)号:US20170089892A1
公开(公告)日:2017-03-30
申请号:US15311309
申请日:2015-05-15
发明人: Anahit AGHVANYAN , Eli N. GLEZER , John KENTEN , George SIGAL , Martin STENGELIN , David ROUTENBERG
IPC分类号: G01N33/543 , C12Q1/68
CPC分类号: G01N33/54306 , C12Q1/6804 , C12Q1/6832 , C12Q1/6837 , C12Q1/6844 , C12Q2525/197 , C12Q2531/125 , C12Q2563/107 , C12Q2565/514
摘要: The present invention is directed to methods for improving assay specificity and performance in binding assays.
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