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公开(公告)号:US20230092143A1
公开(公告)日:2023-03-23
申请号:US17814815
申请日:2022-07-25
Applicant: MOEHS IBERICA, S.L.
Inventor: Abdeslam AKHATOU , Alicia DOBARRO RODRÍGUEZ
IPC: C07D401/12 , C07C201/14 , C07D239/34 , C07D239/36
Abstract: A method is for the synthesis of 2,4-dimethylpyrimidin-5-ol, which can be used as an intermediate compound in the synthesis of Lemborexant. The method includes reacting a nitrophenyl compound with N,N-dimethylformamide diethyl acetal.