公开(公告)号：US09273088B2

公开(公告)日：2016-03-01

申请号：US14055883

申请日：2013-10-17

Applicant: Macau University of Science and Technology

Inventor： Jingrong Wang ,  Pei Luo ,  Hua Zhou ,  Wai In Chan ,  Liang Liu ,  Zhihong Jiang

IPC: A61K31/704 ,  C07J17/00

CPC classification number: C07J17/005 ,  A61K31/704

Abstract: The present invention provides novel ginsenoside derivative compounds and the use thereof in protection against ischemia/reperfusion injury.

Abstract translation: 本发明提供新型人参皂苷衍生物化合物及其在防止缺血/再灌注损伤中的应用。

公开(公告)号：US10342777B2

公开(公告)日：2019-07-09

申请号：US14872198

申请日：2015-10-01

Applicant: Macau University of Science and Technology

Inventor： Pei Luo ,  Zhifeng Zhang ,  Hao Zhang

IPC: A61K31/357 ,  A61K31/216 ,  A61K36/28

Abstract: A caffeoylquinic acid-rich extract obtained from Erigeron multiradiatus and a method for producing the same. A caffeoylquinic acid-rich extract includes at least 15% by weight of a mixture of certain caffeoylquinic acids. The extract with the mixture of caffeoylquinic acids is highly efficacious in treating and preventing myocardial ischemia or myocardial ischemia reperfusion injuries. A method for treating or preventing a disease caused by myocardial ischemia or myocardial ischemia reperfusion includes administering a therapeutically effective amount of the caffeoylquinic acid-rich extract to a subject. Pharmaceutical compositions including the caffeoylquinic acid-rich extract are also disclosed.

公开(公告)号：US20170095443A1

公开(公告)日：2017-04-06

申请号：US14872198

申请日：2015-10-01

Applicant: Macau University of Science and Technology

Inventor： Pei Luo

IPC: A61K31/357 ,  A61K36/28 ,  A61K31/216

CPC classification number: A61K31/357 ,  A61K31/216 ,  A61K36/28 ,  A61K2300/00

Abstract: A caffeoylquinic acid-rich extract obtained from Erigeron multiradiatus and a method for producing the same. A caffeoylquinic acid-rich extract includes at least 15% by weight of a mixture of certain caffeoylquinic acids. The extract with the mixture of caffeoylquinic acids is highly efficacious in treating and preventing myocardial ischemia or myocardial ischemia reperfusion injuries. A method for treating or preventing a disease caused by myocardial ischemia or myocardial ischemia reperfusion includes administering a therapeutically effective amount of the caffeoylquinic acid-rich extract to a subject. Pharmaceutical compositions including the caffeoylquinic acid-rich extract are also disclosed.