公开(公告)号：US11866704B2

公开(公告)日：2024-01-09

申请号：US17247265

申请日：2020-12-06

Applicant: Macau University of Science and Technology

Inventor： Zhi-Hong Jiang ,  Kai-Yue Cao ,  Yu Pan ,  Tong-Meng Yan

IPC: C12N15/113

CPC classification number: C12N15/113 ,  C12N2310/14 ,  C12N2310/32

Abstract: A method of treating a subject suffering from cancer comprising a step of administering an effective amount of a group of double-stranded RNA molecules to the subject, wherein the RNA molecule is isolated or derived from a bacteria of the genus Escherichia. A method of inhibiting growth or proliferation of cancer cells comprising a step of contacting said cells with said RNA molecule; and a pharmaceutical composition for treating cancer comprising said RNA molecule and a pharmaceutically tolerable excipient. Also a double-stranded RNA molecule and a recombinant vector comprising the double-stranded RNA molecule.

公开(公告)号：US20200071695A1

公开(公告)日：2020-03-05

申请号：US16120606

申请日：2018-09-04

Applicant: Macau University of Science and Technology

Inventor： Zhi-Hong Jiang ,  Tong-Meng Yan ,  Kai-Yue CAO

IPC: C12N15/113 ,  A61P35/00

Abstract: A method of treating a subject suffering from cancer includes administering an effective amount of a RNA molecule to the subject, wherein the RNA molecule is isolated or derived from a plant of the genus Taxus. A method of inhibiting growth or proliferation of cancer cells includes contacting cancer cells with the RNA molecule; and a pharmaceutical composition for treating cancer includes the RNA molecule and a pharmaceutically tolerable excipient. Also a double-stranded RNA molecule and a recombinant vector include the double-stranded RNA molecule.

公开(公告)号：US11149271B2

公开(公告)日：2021-10-19

申请号：US16120606

申请日：2018-09-04

Applicant: Macau University of Science and Technology

Inventor： Zhi-Hong Jiang ,  Tong-Meng Yan ,  Kai-Yue Cao

IPC: C12N15/113 ,  A61P35/00

Abstract: A method of treating a subject suffering from cancer includes administering an effective amount of a RNA molecule to the subject, wherein the RNA molecule is isolated or derived from a plant of the genus Taxus. A method of inhibiting growth or proliferation of cancer cells includes contacting cancer cells with the RNA molecule; and a pharmaceutical composition for treating cancer includes the RNA molecule and a pharmaceutically tolerable excipient. Also a double-stranded RNA molecule and a recombinant vector include the double-stranded RNA molecule.