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公开(公告)号:US20190060273A1
公开(公告)日:2019-02-28
申请号:US15682564
申请日:2017-08-22
Applicant: Macau University of Science and Technology
IPC: A61K31/357 , A61K31/352 , A61K9/00 , A61K9/20
Abstract: One example embodiment relates to a method of increasing bioavailability of silybin in a person. The method includes providing silybin and a flavonoid to the person, wherein the flavonoid is tangeretin or baicalein. Another example embodiment relates to a method of treating chronic liver disease in a person by administering silybin and a flavonoid to the person to treat the chronic liver disease.
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公开(公告)号:US20190183856A1
公开(公告)日:2019-06-20
申请号:US15846129
申请日:2017-12-18
Applicant: Macau University of Science and Technology
Inventor: Wenzhe MA , Ying XIE , Xiaolin LIAO , Jiajun HUANG , Wanjun LIN , Ze LONG
IPC: A61K31/381 , A61P35/00 , G01N33/574
CPC classification number: A61K31/381 , A61P35/00 , G01N33/57419 , G01N2333/4748
Abstract: One embodiment relates to a method of treating cancer by administering a compound of Formula I to a patient. Another embodiment relates to a method of treating a patient having cancer associated p53 mutation that includes administering to a patient the compound represented by the Formula I:
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公开(公告)号:US20170143668A1
公开(公告)日:2017-05-25
申请号:US15415883
申请日:2017-01-26
Applicant: Macau University of Science and Technology
Inventor: Wen-zhe MA , Sen-ling FENG , Xiao-jun YAO , Zhong-wen YUAN , Liang LIU , Ying XIE
IPC: A61K31/366 , A61K31/704 , A61K31/337
CPC classification number: A61K31/366 , A61K31/337 , A61K31/352 , A61K31/704 , A61K45/06 , A61K2300/00
Abstract: The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus methoxyflavone is nobiletin. A method of treating multidrug resistance cancer comprising administrating citrus methoxyflavone and a chemotherapeutic drug is also disclosed.
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公开(公告)号:US20170027901A1
公开(公告)日:2017-02-02
申请号:US14848358
申请日:2015-09-09
Applicant: Macau University of Science and Technology
Inventor: Wen-zhe MA , Sen-ling FENG , Xiao-jun YAO , Zhong-wen YUAN , Liang LIU , Ying XIE
IPC: A61K31/353 , A61K31/704 , A61K31/337
CPC classification number: A61K31/366 , A61K31/337 , A61K31/352 , A61K31/704 , A61K45/06 , A61K2300/00
Abstract: The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus methoxyflavone is nobiletin. A method of treating multidrug resistance cancer comprising administrating citrus methoxyflavone and a chemotherapeutic drug is also disclosed.
Abstract translation: 本发明公开了一种治疗多药耐药性的药物组合物,其包含柑橘类甲氧基黄酮和化学治疗药物,其中柑橘类甲氧基黄酮是诺贝利林。 还公开了一种治疗多药耐药性的方法,其包括施用柑橘甲氧基黄酮和化疗药物。
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公开(公告)号:US20170027900A1
公开(公告)日:2017-02-02
申请号:US14848360
申请日:2015-09-09
Applicant: Macau University of Science and Technology
Inventor: Wen-zhe MA , Sen-ling FENG , Xiao-jun YAO , Zhong-wen YUAN , Liang LIU , Ying XIE
IPC: A61K31/352 , A61K31/704 , A61K31/337
CPC classification number: A61K31/352 , A61K31/337 , A61K31/704 , A61K45/06 , A61K2300/00
Abstract: The present invention discloses a pharmaceutical composition of treating multidrug resistance cancer, comprising a citrus methoxyflavone and a chemotherapeutic drug, in which the citrus methoxyflavone is tangeretin. A method of treating multidrug resistance cancer comprising administrating citrus methoxyflavone and a chemotherapeutic drug is also disclosed.
Abstract translation: 本发明公开了一种治疗多药耐药性的药物组合物,其包含柑橘类甲氧基黄酮和化学治疗药物,其中柑橘类甲氧基黄酮为甜菜碱。 还公开了一种治疗多药耐药性的方法,其包括施用柑橘甲氧基黄酮和化疗药物。
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