公开(公告)号：US07723547B2

公开(公告)日：2010-05-25

申请号：US12092684

申请日：2006-10-31

申请人： Martin Ernst ,  Steffen Oehlenschläger ,  Frank Kuhnke ,  Karl-Heinz Roβ ,  Ronald Deeg ,  Johann-Peter Melder

发明人： Martin Ernst ,  Steffen Oehlenschläger ,  Frank Kuhnke ,  Karl-Heinz Roβ ,  Ronald Deeg ,  Johann-Peter Melder

IPC分类号： C07C209/48

CPC分类号： B01J8/20 ,  B01D3/14 ,  B01J2219/00006 ,  B01J2219/00029 ,  B01J2219/0004 ,  C07C209/48 ,  C07C211/11

摘要： The present invention relates to a process for the industrial preparation of a diamine starting from a corresponding alkenyl nitrile comprising at least one C—C double bond, which comprises the steps (a) reaction of the alkenyl nitrile with a corresponding monoamine in a first reactor so that the monoamine adds exothermically onto the at least one double bond to form an aminoalkyl nitrile, with the monoamine and water being charged initially and the alkenyl nitrile being fed in; (b) evaporation of unreacted alkenyl nitrile and monoamine to increase the concentration of the aminoalkyl nitrile product in the bottoms of the first reactor; (c) transfer of the aminoalkyl nitrile bottom product from step (b) to a second reactor; (d) batchwise catalytic hydrogenation of the aminoalkyl nitrile transferred in step (c) to the diamine in the second reactor, with each batch being obtained by initially charging a catalyst suitable for the hydrogenation of nitriles to amines and also water, the desired diamine and a base, introducing hydrogen into the second reactor and feeding in the aminoalkyl nitrile transferred in step (c); and (e) isolation of the diamine and, if appropriate, repetition of the steps (a) to (e). The invention further relates to an apparatus for preparing these diamines and the use of the apparatuses. A preferred diamine is 3-dimethylaminopropylamine (DMAPA).

摘要翻译： 本发明涉及从包含至少一个C-C双键的相应链烯基腈开始工业制备二胺的方法，其包括步骤（a）在第一反应器中烯基腈与相应的单胺反应 使得单胺在至少一个双键上放热添加以形成氨基烷基腈，最初加入单胺和水，并加入链烯基腈; （b）蒸发未反应的烯基腈和单胺以增加第一反应器底部氨基烷基腈产物的浓度; （c）将氨基烷基腈底部产物从步骤（b）转移至第二反应器; （d）将步骤（c）中转移的氨基烷基腈分批催化氢化为第二反应器中的二胺，每个批次通过首先将适合于将腈氢化成的催化剂加入到胺中而得到，并且还需要水，所需的二胺和 碱，将氢气引入第二反应器并进料步骤（c）中转移的氨基烷基腈; 和（e）分离二胺，如果合适，重复步骤（a）至（e）。 本发明还涉及一种用于制备这些二胺的装置和该装置的用途。 优选的二胺是3-二甲基氨基丙胺（DMAPA）。