公开(公告)号：US20210380513A1

公开(公告)日：2021-12-09

申请号：US17303462

申请日：2021-05-28

Applicant: McMaster University

Inventor： Jake Magolan ,  Nick Jentsch ,  Xiong Zhang ,  Mathew Piotrowski ,  Partick Darveau ,  Meghan Fragis ,  Jarrod Johnson ,  Nikki Ritchie ,  Arnav Kaul

IPC: C07C37/14 ,  C07J7/00 ,  B01J21/04 ,  C07D209/08 ,  C07C41/26 ,  C07C253/30 ,  C07C201/12 ,  C07J1/00 ,  C07D311/30 ,  C07D311/32 ,  C07D307/80

Abstract: The present application describes process for preparing an ortho-allylated hydroxy aryl compounds such as compounds of Formula (I) by reacting an allylic alcohol with a hydroxy aryl compound in the presence of aluminum compound selected from alumina and aluminum alkoxides and in a non-protic solvent wherein at least one carbon atom ortho to the hydroxy group in the hydroxy aryl compound is unsubstituted. The present application also includes compounds of Formula (I).