公开(公告)号：US20230310061A1

公开(公告)日：2023-10-05

申请号：US18295416

申请日：2023-04-04

Applicant: Medtronic, Inc.

Inventor： Mark T. Stewart ,  Lars M. Mattison ,  Brian T. Howard ,  Damijan Miklavcic ,  Tadej Kotnik ,  Janja Dermol-Cerne ,  Tina Batista Napotnik

IPC: A61B18/12

CPC classification number: A61B18/1206 ,  A61B2017/00176

Abstract: A method of delivering pulsed electric field energy to perform ablation of a tissue includes providing a pulse train to an electrode. The pulse train may include a first set of pulses with a first pulse width to generate first electric field and a second set of pulses with a second pulse width greater than the first pulse width to generate a second electric field. The electrode may be positioned at a same position during generation of the first electric field and the second electric field. The first electric field may be configured to have a higher electroporation effect on the first elongated cells having a first orientation than on second elongated cells having a second orientation. The second electric field may be configured to have a higher electroporation effect on the second cells than on the first cells.