公开(公告)号：US09347885B2

公开(公告)日：2016-05-24

申请号：US13889306

申请日：2013-05-07

申请人： Mohamad Saleh Al Salhi ,  Vadivel Masilamani ,  Farjah Hassan Algahtani

发明人： Mohamad Saleh Al Salhi ,  Vadivel Masilamani ,  Farjah Hassan Algahtani

IPC分类号： G01N21/64 ,  G01N33/48 ,  G01N33/49 ,  G01N33/68

CPC分类号： G01N21/6486 ,  G01N33/492 ,  G01N33/6812

摘要： The method of detecting thalassemia by optical analysis of blood components is a spectral detection method that is based on the fluorescence spectra of a set of biomolecules, including tyrosine, tryptophan, nicotinamide adenine dinucleotide, and flavin adenine dinucleotide, which are all found in blood plasma, and porphyrin, which is found in red blood cells (RBCs). Measured ratios of intensity maxima between tryptophan and nicotinamide adenine dinucleotide, flavin adenine dinucleotide and nicotinamide adenine dinucleotide, tyrosine and tryptophan, and the normal form of porphyrin and the basic form of porphyrin may each be used, alone or in combination, to diagnose a patient as suffering from thalassemia.

摘要翻译： 通过血液成分的光学分析检测地中海贫血的方法是基于一组生物分子的荧光光谱的光谱检测方法，包括酪氨酸，色氨酸，烟酰胺腺嘌呤二核苷酸和黄素腺嘌呤二核苷酸，其均在血浆中发现 和卟啉，其在红细胞（RBC）中发现。 色氨酸和烟酰胺腺嘌呤二核苷酸，黄素腺嘌呤二核苷酸和烟酰胺腺嘌呤二核苷酸，酪氨酸和色氨酸之间的强度最大值和卟啉的正常形式和卟啉的基本形式的测量比可以单独或组合地用于诊断患者 因为患有地中海贫血。