公开(公告)号：US10117953B2

公开(公告)日：2018-11-06

申请号：US15284444

申请日：2016-10-03

Applicant: Novartis AG

Inventor： Tinya Abrams ,  Steven Bruce Cohen ,  Christie P. Fanton ,  Thomas Huber ,  Kathy Miller ,  Siew Ho Schleyer ,  Kathrin Ulrike Tissot-Daguette ,  Catrin Finner

IPC: A61K47/48 ,  A61K47/68 ,  A61K45/06 ,  C07K16/28 ,  A61K31/537 ,  A61K47/12 ,  A61K47/26 ,  A61K9/19 ,  A61K9/00 ,  A61K49/00 ,  A61K51/10 ,  C07K16/32 ,  A61K39/00

Abstract: The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.