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公开(公告)号:US20050101526A1
公开(公告)日:2005-05-12
申请号:US11018311
申请日:2004-12-22
申请人: Olaf Wilhelm , Horst Kessler , Markus Burgle , Nils Potthoff , Niko Schmiedeberg
发明人: Olaf Wilhelm , Horst Kessler , Markus Burgle , Nils Potthoff , Niko Schmiedeberg
CPC分类号: C12N9/6462 , A61K38/00 , C07K7/64 , C12Y304/21073
摘要: The present invention relates to cyclic peptides as inhibitors of urokinase binding to the urokinase receptor. Said cyclic peptides are suitable as pharmaceutical active substances for disorders mediated by urokinase and its receptor.
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公开(公告)号:US20070244127A1
公开(公告)日:2007-10-18
申请号:US11631891
申请日:2005-09-20
申请人: Wolfgang Schmalix , Markus Burgle , Klaus Koch
发明人: Wolfgang Schmalix , Markus Burgle , Klaus Koch
CPC分类号: A61K31/198 , A61K9/0019 , A61K31/18 , A61K31/495 , A61K47/10 , A61K47/12
摘要: The invention relates to improved and stable pharmaceutical formulations of phenylalanine derivatives and the use thereof as urokinase inhibitors, particularly for the treatment of malignant tumors and tumoral metastases.
摘要翻译: 本发明涉及苯丙氨酸衍生物的改进和稳定的药物制剂及其作为尿激酶抑制剂的用途,特别是用于治疗恶性肿瘤和肿瘤转移。
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