公开(公告)号：US20180148685A1

公开(公告)日：2018-05-31

申请号：US15543021

申请日：2016-01-12

Applicant: Osaka University

Inventor： Kohji Nishida ,  Yuzuru SASAMOTO ,  Ryuhei HAYASHI

IPC: C12N5/071 ,  C12N15/86 ,  C07K14/47

Abstract: The present invention relates to a method for inducing a keratin 12-positive corneal epithelioid cell from a surface ectoderm-derived cell. More specifically, the present invention relates to a method for inducing a keratin 12-positive corneal epithelioid cell, comprising introducing PAX6, KLF4, and OCT4 into a surface ectoderm-derived cell, such as an oral mucosal epithelial cell, and a corneal epithelioid cell induced by the method.