公开(公告)号：US09428455B2

公开(公告)日：2016-08-30

申请号：US14688451

申请日：2015-04-16

Applicant: Pfizer Inc.

Inventor： Renuka Devi Reddy ,  Evgenyi Shalaev ,  Ravi Mysore Shanker ,  Carl Bernard Ziegler

IPC: C07D207/34 ,  A61K31/40

CPC classification number: C07D207/34 ,  A61K31/40

Abstract: Processes for annealing amorphous atorvastatin is described. Pharmaceutical compositions and formulations containing annealed amorphous atorvastatin are also described.

公开(公告)号：US09932307B2

公开(公告)日：2018-04-03

申请号：US15220897

申请日：2016-07-27

Applicant: Pfizer Inc.

Inventor： Renuka Devi Reddy ,  Evgenyi Shalaev ,  Ravi Mysore Shanker ,  Carl Bernard Ziegler

IPC: C07D207/34 ,  A61K31/40

CPC classification number: C07D207/34 ,  A61K31/40

Abstract: Processes for annealing amorphous atorvastatin is described. Pharmaceutical compositions and formulations containing annealed amorphous atorvastatin are also described.

公开(公告)号：US20160332965A1

公开(公告)日：2016-11-17

申请号：US15220897

申请日：2016-07-27

Applicant: Pfizer Inc.

Inventor： Renuka Devi Reddy ,  Evgenyi Shalaev ,  Ravi Mysore Shanker ,  Carl Bernard Ziegler

IPC: C07D207/34 ,  A61K31/40

CPC classification number: C07D207/34 ,  A61K31/40

Abstract: Processes for annealing amorphous atorvastatin is described. Pharmaceutical compositions and formulations containing annealed amorphous atorvastatin are also described.

公开(公告)号：US20150274659A1

公开(公告)日：2015-10-01

申请号：US14688451

申请日：2015-04-16

Applicant: Pfizer Inc.

Inventor： Renuka Devi Reddy ,  Evgenyi Shalaev ,  Ravi Mysore Shanker ,  Carl Bernard Ziegler

IPC: C07D207/34

CPC classification number: C07D207/34 ,  A61K31/40

Abstract: Processes for annealing amorphous atorvastatin is described. Pharmaceutical compositions and formulations containing annealed amorphous atorvastatin are also described.

Abstract translation: 描述了退火无定形阿托伐他汀的方法。 还描述了含有退火的无定形阿托伐他汀的药物组合物和制剂。