-
公开(公告)号:US4557931A
公开(公告)日:1985-12-10
申请号:US446231
申请日:1982-12-02
IPC分类号: A61K9/127 , A61K39/00 , G01N33/574
CPC分类号: A61K9/1271 , A61K39/0011 , G01N33/574 , G01N33/57469 , A61K2039/6081 , Y10S435/96 , Y10S435/961
摘要: GM2 is a ganglioside present on the surface of tumors and stimulates an appreciable immune response in mammals. It is useful when coupled with a non-toxic protein carrier or mixed with an adjuvent and injected parenterally of raising the anti-GM2 titer in serum. GM2 is also valuable as a diagnostic agent.
摘要翻译: GM2是存在于肿瘤表面的神经节苷脂,并且在哺乳动物中刺激明显的免疫应答。 当与无毒蛋白质载体偶联或与佐剂混合并且肠胃外注射以提高血清中的抗GM2滴度时,它是有用的。 GM2也作为诊断剂有价值。