公开(公告)号：US3845072A

公开(公告)日：1974-10-29

申请号：US19492671

申请日：1971-11-02

Applicant: SNAM PROGETTI

Inventor： ROMANO U ,  MAOGGI P ,  MAURI M

IPC: C07D209/08 ,  C07D27/56

CPC classification number: C07D209/08

Abstract: A-N=C(-R)-B

WHEREIN N IS NITROGEN; C IS CARBONIUM; R IS A MEMBER OF THE GROUP CONSISTING OF HYDROGEN, LOWER ALKYL, LOWER ALKENYL AND CARBOCYCLIC MONOCYCLIC ARYL; A AND B ARE MEMBERS OF THE GROUP CONSISTING OF LOWER ALKYL LOWER ALKENYL, MONOCYCLIC CARBOCYCLIC ARLY AND ARALKYL REPRESENTED BY CH3C6H.4 AND C2H5H.4, ARE CAUSED TO REACT INTHE VAPORR PHASE BY HEATING SAID OXYGEN AND IMINE TOGETHER IN THE MOLAR RANGE FROM 0.2:01 TO 10:1 TO A TEMPERATURE IN THE RANGE OFF 300* TO 800* C. FOR A TIME RANGING FROM 0.1 TO 20 SECONDS IN THE PRESENCE OF ACTIVATED SILICA AND STEAM.
1. A PROCESS FOR THE PRODUCTION OF HIGH YIELDS OF INDOLE AND ALKYL, ARALKYL AND PHENYL SUBSTITUTED INDOLES THROUGH THE OXIDATIVE DEHYDROCYCLIZATION OF IMINES WHEREIN OXYGEN AND THE CORRESPONDING IMINE RE MULA