公开(公告)号：US20250049885A1

公开(公告)日：2025-02-13

申请号：US18782811

申请日：2024-07-24

Applicant: SOUTH DAKOTA BOARD OF REGENTS

Inventor： TUGBA OZDEMIR ,  BETH BLAKE

IPC: A61K38/17 ,  A61K47/54 ,  A61L26/00 ,  A61L27/10 ,  A61L27/34

Abstract: Articles, such as implants and medical devices, treated with a hyaluronic acid binding peptide are provided. Articles are coated with a surface functionalizing agent which bind to and immobilize the hyaluronic acid binding peptide. Methods of improving and/or reducing foreign body reaction to an article are also provided, as are methods of decreasing inflammation, promoting wound healing, and treating dermal conditions.