公开(公告)号：US3919048A

公开(公告)日：1975-11-11

申请号：US45923674

申请日：1974-04-08

Applicant: STAMICARBON

Inventor： DAHLMANS JOHANNES J ,  MEIJERINK THEO A J

IPC: C12N11/00 ,  C12N11/02 ,  C12N11/16 ,  C07G7/02

CPC classification number: C12N11/02

Abstract: Insoluble enzyme complexes are prepared by chemically bonding enzymes to natural sponge. The enzyme can be either directly bonded to the sponge, or the sponge can be first modified with an appropriate chemical reagent, such as a cyclic dicarboxylic acid anhydride, prior to chemical bonding with the enzyme.

Abstract translation: 通过将酶化学键合到天然海绵中制备不溶性酶复合物。 酶可以直接结合到海绵上，或者在与酶化学键合之前，可以用适当的化学试剂如环状二羧酸酐修饰海绵。

公开(公告)号：US3905988A

公开(公告)日：1975-09-16

申请号：US11631171

申请日：1971-02-18

Applicant: STAMICARBON

Inventor： DAHLMANS JOHANNES J ,  BOESTEN WILHELMUS H J

IPC: C07D263/46 ,  C07D263/52 ,  C07D85/26

CPC classification number: C07D263/52 ,  C07D263/46

Abstract: A process for the preparation of 2-thionoxazolidone-5 and derivatives thereof is disclosed wherein tertiary alkyl esters of secondary amino carboxylic acid or the N-thiocarbonyl chloride of an Alpha -secondary aminocarboxylic acid is subjected to the action of a proton yielding acid. The compounds produced by the process of this invention are useful as amino acid derivatives in the synthesis of peptides.

Abstract translation: 公开了制备2-硫代恶唑烷酮-5及其衍生物的方法，其中仲氨基羧酸的叔烷基酯或α-仲氨基羧酸的N-硫代羰基氯经受质子产生酸的作用。 通过本发明方法生产的化合物可用作肽合成中的氨基酸衍生物。