公开(公告)号：US3780083A

公开(公告)日：1973-12-18

申请号：US3780083D

申请日：1972-02-14

Applicant: STAMICARBON

Inventor： DEUMENS J ,  STIJFS P

IPC: C07C20060101 ,  C07C121/02 ,  C07C121/34

CPC classification number: C07C255/00 ,  Y02P20/582

Abstract: SCHIFF BASES DERIVED FROM BUTANONE AND AN ALIPHATIC PRIMARY AMINE ARE CATALYSTS IN THE PREPARATION OF A-MONOCYANOETHYLATED BUTANONE BY REACTING ACRYLONITRILE WITH AT LEAST AN EQUIMOLAR QUANTITY OF ACRYLONITRILE IN THE PRESENCE OF AN ACID. THE A-MONO-CYANOETHYLATED BUTANONES, SUCH AS 4-METHYL-5-OXOHEXANE NITRILE AND 5-OXOHEPTANE NITRILE ARE PRODUCED WITH ONLY MINOR AMOUNTS OF CONTAMINANT''S THAT ARE EASILY REMOVED. THE A-MONO-CYANOETHYLATED BUTANONES ARE USEFUL FOR THE PREPARATION OF DIAMINES, KETOCARBOXYLIC ACIDS OR KETO-AMIDES.

公开(公告)号：US3728353A

公开(公告)日：1973-04-17

申请号：US3728353D

申请日：1970-07-10

Applicant: STAMICARBON

Inventor： STIJFS P ,  GROEN S ,  DEUMENS J

IPC: C07D295/02 ,  C07D295/027 ,  C07D29/06

CPC classification number: C07D295/027

Abstract: A process for the preparation of a carbon-substituted piperidine by the hydrogenation of a N-substituted gamma -cyanoketoimine in the presence of a hydrogenation catalyst, is disclosed. A primary amine having the same substituent as the nitrogen atom of the starting gamma -cyanoketoimine is receovered in high yield from the reaction mixture. The carbon substituted piperidines thus produced are useful as starting materials for the production of herbicides or pharmaceuticals.

Abstract translation: 公开了在氢化催化剂存在下通过氢化N-取代的γ-氰基酮亚胺制备碳取代的哌啶的方法。 具有与起始γ-氰基酮亚胺的氮原子相同的取代基的伯胺以高产率从反应混合物中回收。 如此制备的碳取代的哌啶可用作生产除草剂或药物的原料。