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公开(公告)号：US08889685B2
公开(公告)日：2014-11-18
申请号：US13928571
申请日：2013-06-27
Applicant: Sunovion Pharmaceuticals Inc.
Inventor： H. Scott Wilkinson , Richard Hsia , Tushar Misra , Kostas Saranteas , Patrick Mousaw
IPC: A61K31/444 , A61K31/495 , A61K31/4985 , C07D213/61 , C07D295/182 , C07D471/04 , C07D487/04
CPC classification number: C07D487/04 , C07C57/145
Abstract: Maleate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided. The salts are useful for treating sleep disorders.
Abstract translation: （6-（5-氯-2-吡啶基）-5 - [（4-甲基-1-哌嗪基）羰氧基] -7-氧代-6,7-二氢-5H-吡咯并[3,4-b ]吡嗪）。 这些盐可用于治疗睡眠障碍。
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![Besylate Salts of 6-(5-Chloro-2-Pyridyl)-5-[(4-Methyl-1-Piperazinyl)Carbonyloxy]-7-oxo-6,7-dihydro-5H-Pyrrolo[3,4-b]Pyrazine](/abs-image/US/2013/10/31/US20130289039A1/abs.jpg.150x150.jpg)
公开(公告)号：US20130289039A1
公开(公告)日：2013-10-31
申请号：US13927439
申请日：2013-06-26
Applicant: Sunovion Pharmaceuticals Inc.
Inventor： Richard Hsia , H. Scott WILKINSON , Tushar Misra , Kostas Saranteas , Patrick Mousaw
IPC: C07D487/04
CPC classification number: C07D487/04
Abstract: A novel besylate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.
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3.发明授权Method of decreasing the bitterness of a pharmaceutical dosage form containing zopiclone 有权降低含有佐匹克隆的药物剂型的苦味的方法公开(公告)号：US08889686B2
公开(公告)日：2014-11-18
申请号：US13932324
申请日：2013-07-01
Applicant: Sunovion Pharmaceuticals Inc.
Inventor： H. Scott Wilkinson , Richard Hsia , Tushar Misra , Kostas Saranteas , Patrick Mousaw
IPC: A61K31/44 , A61K31/495 , A61K31/4985 , C07D213/61 , C07D295/182 , C07D471/04 , C07D487/04 , C07C59/245
CPC classification number: C07D487/04 , C07C59/245
Abstract: L malate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are disclosed for decreasing the bitterness of eszopiclone dosage forms
Abstract translation: （6-（5-氯-2-吡啶基）-5 - [（4-甲基-1-哌嗪基）羰基氧基] -7-氧代-6,7-二氢-5H-吡咯并[3,4- b]吡嗪）用于降低右佐佐单抗剂型的苦味
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4.发明授权Method for treating anxiety with a dosage form of besylate salts of zopiclone or eszopiclone 有权用佐匹克隆或替佐氟隆的苯磺酸盐剂型治疗焦虑症的方法公开(公告)号：US08809332B2
公开(公告)日：2014-08-19
申请号：US13927439
申请日：2013-06-26
Applicant: Sunovion Pharmaceuticals Inc.
Inventor： Richard Hsia , H. Scott Wilkinson , Tushar Misra , Kostas Saranteas , Patrick Mousaw
IPC: A61K31/444 , A61K31/495 , A61K31/4985 , C07D213/61 , C07D295/182 , C07D471/04
CPC classification number: C07D487/04
Abstract: Besylate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided.
Abstract translation: -5 - [（4-甲基-1-哌嗪基）羰氧基] -7-氧代-6,7-二氢-5H-吡咯并[3,4-b ]吡嗪）。
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