公开(公告)号：US10358438B2

公开(公告)日：2019-07-23

申请号：US15329615

申请日：2015-07-20

申请人： THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

发明人： Jon T. Njardarson ,  Isaac Chogii ,  David Townsend Smith ,  Edon Vitaku

IPC分类号： C07D405/04 ,  C07D209/42 ,  C07D207/48 ,  C07D207/18 ,  C07D207/277 ,  C07D209/12

摘要： The present invention relates to various organic reactions including a method for producing heterocyclic compounds using a [3+2] annulation; a method for producing fluorinated heteroaromatic compounds; and a method for alkylating a meta-position of a phenolic compound.

公开(公告)号：US20160042156A1

公开(公告)日：2016-02-11

申请号：US14820577

申请日：2015-08-07

申请人： THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

发明人： Jon T. Njardarson ,  David T. Smith ,  Edon Vitaku

IPC分类号： G06F19/00 ,  G06F17/30 ,  G06Q30/00

CPC分类号： G16H10/40 ,  G06F16/24575 ,  G06Q30/018

摘要： The present invention provides a method for conducting a drug discovery research by identifying a lead candidate based solely on drugs that have been approved for a clinical use by an agency who has the authority to approve a drug for clinical use in mammal. The method uses a cheminformatics database. The present invention also provides a method and system for analyzing chemical drugs that have been approved for clinical use.

摘要翻译： 本发明提供了一种通过仅通过具有批准用于哺乳动物临床使用的药物的机构批准用于临床使用的药物来鉴定首席候选者的药物发现研究的方法。 该方法使用化学信息数据库。 本发明还提供了用于分析已被批准用于临床应用的化学药物的方法和系统。