专利检索 ap:("THE JOHNS HOPKINS UNIVERSITY") AND inv:"Mohamad Allaf" 第 1 页

1.

发明授权
Nuclear imaging and radiotherapeutics agents targeting carbonic anhydrase IX and uses thereof 有权

公开(公告)号：US10857246B2

公开(公告)日：2020-12-08

申请号：US15578473

申请日：2016-06-01

申请人： THE JOHNS HOPKINS UNIVERSITY

发明人： Xing Yang , Il Minn , Steven Rowe , Sangeeta Ray , Ronnie C. Mease , Michael Gorin , Mohamad Allaf , Martin G. Pomper

IPC分类号： A61K51/04 , C07D417/14 , C07D417/12 , A61P35/00

摘要： Highly potent and selective radionuclide-based imaging and therapy agents targeting carbonic anhydrase IX with minimum non-specific organ uptake are disclosed. Methods of imaging and/or treating carbonic anhydrase IX-expressing cells or tumors also are disclosed.