公开(公告)号：US20190062838A1

公开(公告)日：2019-02-28

申请号：US16181093

申请日：2018-11-05

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  RIKEN ,  NSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ ,  U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

发明人： Antonio V. Delgado-Escueta ,  Kazuhiro Yamakawa ,  Toshimitsu Suzuki ,  Marco Tulio Medina-Hernandez ,  Maria Elisa Alonso Vilatela

IPC分类号： C12Q1/6883 ,  C07K16/18 ,  A61K31/19

摘要： Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.

公开(公告)号：US20160076105A1

公开(公告)日：2016-03-17

申请号：US14951407

申请日：2015-11-24

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  RIKEN ,  INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ ,  U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

发明人： Antonio V. Delgado-Escueta ,  Kazuhiro Yamakawa ,  Toshimitsu Suzuki ,  Marco Tulio Medina-Hernandez ,  Maria Elisa Alonso Vilatela

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  A61K31/19 ,  C07K16/18 ,  C12Q2600/118 ,  C12Q2600/156 ,  C12Q2600/172

摘要： Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.

摘要翻译： 提供了用EFHC1，EFHC1激动剂或EFHC1类似物诊断或治疗癫痫病的组合物和方法。 提供了EFHC1a，EFHC1a激动剂或EFHC1a类似物诊断或治疗癫痫病的组合物和方法。

公开(公告)号：US20210180136A1

公开(公告)日：2021-06-17

申请号：US17248798

申请日：2021-02-08

申请人： Marco Tulio Medina-Hernandez ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  RIKEN ,  INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ ,  U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

发明人： Antonio V. Delgado-Escueta ,  Kazuhiro Yamakawa ,  Toshimitsu Suzuki ,  Marco Tulio Medina-Hernandez ,  Maria Elisa Alonso Vilatela

IPC分类号： C12Q1/6883

摘要： Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.

公开(公告)号：US11932908B2

公开(公告)日：2024-03-19

申请号：US17248798

申请日：2021-02-08

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  RIKEN ,  INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ ,  U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS ,  Marco Tulio Medina-Hernandez

发明人： Antonio V. Delgado-Escueta ,  Kazuhiro Yamakawa ,  Toshimitsu Suzuki ,  Marco Tulio Medina-Hernandez ,  Maria Elisa Alonso Vilatela

IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12Q1/6883

CPC分类号： C12Q1/6883 ,  C12Q2600/118 ,  C12Q2600/156 ,  C12Q2600/172

摘要： Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.

公开(公告)号：US10913980B2

公开(公告)日：2021-02-09

申请号：US16181093

申请日：2018-11-05

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  RIKEN ,  INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ ,  U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

发明人： Antonio V. Delgado-Escueta ,  Kazuhiro Yamakawa ,  Toshimitsu Suzuki ,  Marco Tulio Medina-Hernandez ,  Maria Elisa Alonso Vilatela

IPC分类号： C07H21/04 ,  C12Q1/68 ,  C12Q1/6883

摘要： Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.

公开(公告)号：US10260099B2

公开(公告)日：2019-04-16

申请号：US14951407

申请日：2015-11-24

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ,  RIKEN ,  INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ ,  THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

发明人： Antonio V. Delgado-Escueta ,  Kazuhiro Yamakawa ,  Toshimitsu Suzuki ,  Marco Tulio Medina-Hernandez ,  Maria Elisa Alonso Vilatela

IPC分类号： C07H21/04 ,  C12Q1/68 ,  C12Q1/6883 ,  A61K31/19 ,  C07K16/18

摘要： Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.