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1.发明申请公开(公告)号：US20130109726A1
公开(公告)日：2013-05-02
申请号：US13806370
申请日：2011-06-24
IPC分类号： A61K31/426
CPC分类号： A61K31/426
摘要： The present invention provides a therapeutic or preventive agent for hypertension or normal high blood pressure, and for renal dysfunction, that is more effective than existing drugs.More specifically, the present invention provides a sustained-release pharmaceutical composition for treating or preventing hypertension or normal high blood pressure, and for renal dysfunction, comprising as an active ingredient a 2-phenylthiazole compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof.
摘要翻译： 本发明提供了高血压或正常高血压的治疗或预防剂，对于肾功能障碍，其比现有药物更有效。 更具体地说，本发明提供了用于治疗或预防高血压或正常高血压的缓释药物组合物和用于肾功能障碍的缓释药物组合物，其包含作为活性成分的由下式（I）表示的2-苯基噻唑化合物或药学上可接受的盐 其可接受的盐。
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公开(公告)号：US20110046192A1
公开(公告)日：2011-02-24
申请号：US12823715
申请日：2010-06-25
IPC分类号： A61K31/426 , A61P9/12
CPC分类号： A61K45/06 , A61K31/426 , A61K2300/00
摘要： The present invention relates to a therapeutic drug or a preventive drug for hypertension or high-normal blood pressure, comprising (a) and (b) as active ingredients: (a) a 2-phenylthiazole compound represented by formula (I) or a pharmaceutically acceptable salt thereof; (b) at least one compound or a pharmaceutically acceptable salt thereof selected from the group consisting of calcium antagonists, renin-angiotensin system inhibitors, diuretics, sympatholytic agents, vasodilators, and medicinally acceptable salts of these. The present invention also relates to a therapeutic method or a preventive method for hypertension or high-normal blood pressure, comprising administering the above (a) and (b) in amounts effective for treating or preventing hypertension or high-normal blood pressure.
摘要翻译： 本发明涉及用于高血压或高血压正常的治疗药物或预防药物，其包含（a）和（b）作为活性成分：（a）由式（I）表示的2-苯基噻唑化合物或其药学上可接受的盐 其可接受的盐; （b）至少一种选自钙拮抗剂，肾素 - 血管紧张素系统抑制剂，利尿剂，交感神经溶解剂，血管舒张剂及其医药上可接受的盐的化合物或其药学上可接受的盐。 本发明还涉及高血压或高正常血压的治疗方法或预防方法，包括以有效治疗或预防高血压或高正常血压的量施用上述（a）和（b）。
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公开(公告)号：US09545445B2
公开(公告)日：2017-01-17
申请号：US12823715
申请日：2010-06-25
IPC分类号： A01N43/78 , A61K31/425 , A61K45/06 , A61K31/426
CPC分类号： A61K45/06 , A61K31/426 , A61K2300/00
摘要： The present invention relates to a therapeutic drug or a preventive drug for hypertension or high-normal blood pressure, comprising (a) and (b) as active ingredients: (a) a 2-phenylthiazole compound represented by formula (I) or a pharmaceutically acceptable salt thereof; (b) at least one compound or a pharmaceutically acceptable salt thereof selected from the group consisting of calcium antagonists, renin-angiotensin system inhibitors, diuretics, sympatholytic agents, vasodilators, and medicinally acceptable salts of these. The present invention also relates to a therapeutic method or a preventive method for hypertension or high-normal blood pressure, comprising administering the above (a) and (b) in amounts effective for treating or preventing hypertension or high-normal blood pressure.
摘要翻译： 本发明还涉及高血压或高正常血压的治疗方法或预防方法，包括以有效治疗或预防高血压或高正常血压的量施用上述（a）和（b）。
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