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公开(公告)号:US20070065850A1
公开(公告)日:2007-03-22
申请号:US11501810
申请日:2006-08-10
IPC分类号: C12Q1/68 , G01N33/567
CPC分类号: G01N33/6875 , C12Q1/6883 , C12Q2600/158 , G01N2800/325
摘要: A method for diagnosis of heart failure in a human subject, which comprises the step of: measuring an endoplasmic reticulum (ER)-initiated apoptotic signal such as CHOP in a biological sample originated from the subject is disclosed. According to the invention, by employing the new marker in stead of or in addition to a conventional cardiac marker such as BNP, more accurate diagnosis of heart failure can be attained.
摘要翻译: 公开了一种用于诊断人类受试者心脏衰竭的方法,其包括以下步骤:测量源自受试者的生物样品中的内质网(ER)诱导的凋亡信号如CHOP。 根据本发明,通过采用新的标记物代替常规心脏标志物例如BNP或除常规心脏标志物如BNP之外,可以更准确地诊断心力衰竭。