-
公开(公告)号：US09733257B2
公开(公告)日：2017-08-15
申请号：US15290613
申请日：2016-10-11
Applicant: The Curators of the University of Missouri
Inventor： James L. Cook , Cristi R. Cook , Aaron M. Stoker , Keiichi Kuroki , Bridget Colleen Garner , Richard Evans , Brandon Lee Roller , Prakash Sidha Jayabalan
CPC classification number: G01N33/6887 , C12Q1/6883 , C12Q2600/112 , C12Q2600/136 , G01N33/5308 , G01N2333/52 , G01N2333/5421 , G01N2800/105 , G01N2800/56
Abstract: Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) and determining treatment are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, Apolipoprotein A1, and Apolipoprotein E. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described.
-
公开(公告)号：US09488646B2
公开(公告)日：2016-11-08
申请号：US14175254
申请日：2014-02-07
Applicant: The Curators of the University of Missouri
Inventor： James L. Cook , Cristi R. Cook , Aaron M. Stoker , Keiichi Kuroki , Bridget Colleen Garner , Richard Evans , Brandon Lee Roller , Prakash Sidha Jayabalan
CPC classification number: G01N33/6887 , C12Q1/6883 , C12Q2600/112 , C12Q2600/136 , G01N33/5308 , G01N2333/52 , G01N2333/5421 , G01N2800/105 , G01N2800/56
Abstract: Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) and determining treatment are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, Apolipoprotein A1, and Apolipoprotein E. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described.
Abstract translation: 公开了用于诊断骨关节炎（OA）和确定治疗的生物标志物，生物标志物组和方法，使用来自受试者的测试样品中某些多肽的表达水平的测量，包括MCP1，IL8，KC，MMP2，MMP3，载脂蛋白A1和 载脂蛋白E.还描述了用于监测OA治疗功效，诊断试剂和试剂盒的相关方法。
-
公开(公告)号：US20140155499A1
公开(公告)日：2014-06-05
申请号：US14175254
申请日：2014-02-07
Applicant: The Curators of the University of Missouri
Inventor： James L. Cook , Cristi R. Cook , Aaron M. Stoker , Keiichi Kuroki , Bridget Colleen Garner , Richard Evans , Brandon Lee Roller , Prakash Sidha Jayabalan
IPC: G01N33/53
CPC classification number: G01N33/6887 , C12Q1/6883 , C12Q2600/112 , C12Q2600/136 , G01N33/5308 , G01N2333/52 , G01N2333/5421 , G01N2800/105 , G01N2800/56
Abstract: Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) and determining treatment are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, Apolipoprotein A1, and Apolipoprotein E. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described.
Abstract translation: 公开了用于诊断骨关节炎（OA）和确定治疗的生物标志物，生物标志物组和方法，使用来自受试者的测试样品中某些多肽的表达水平的测量，包括MCP1，IL8，KC，MMP2，MMP3，载脂蛋白A1和 载脂蛋白E.还描述了用于监测OA治疗功效，诊断试剂和试剂盒的相关方法。
-
公开(公告)号：US20170030925A1
公开(公告)日：2017-02-02
申请号：US15290613
申请日：2016-10-11
Applicant: The Curators of the University of Missouri
Inventor： James L. Cook , Cristi R. Cook , Aaron M. Stoker , Keiichi Kuroki , Bridget Colleen Garner , Richard Evans , Brandon Lee Roller , Prakash Sidha Jayabalan
IPC: G01N33/68
CPC classification number: G01N33/6887 , C12Q1/6883 , C12Q2600/112 , C12Q2600/136 , G01N33/5308 , G01N2333/52 , G01N2333/5421 , G01N2800/105 , G01N2800/56
Abstract: Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) and determining treatment are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, Apolipoprotein A1, and Apolipoprotein E. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described.
Abstract translation: 公开了用于诊断骨关节炎（OA）和确定治疗的生物标志物，生物标志物组和方法，使用来自受试者的测试样品中某些多肽的表达水平的测量，包括MCP1，IL8，KC，MMP2，MMP3，载脂蛋白A1和 载脂蛋白E.还描述了用于监测OA治疗功效，诊断试剂和试剂盒的相关方法。
-
-
-
Search Results
4
records
(took 0.015 seconds)
