公开(公告)号：US20220280792A1

公开(公告)日：2022-09-08

申请号：US17702621

申请日：2022-03-23

申请人： The Regents of the University of California ,  U.S. Government Represented by the Department of Veterans Affairs ,  LightSide MD, LLC

发明人： Karunesh GANGULY ,  Adelyn TSU ,  Nikhilesh NATRAJ ,  Gabriel Philip HOWLES-BANERJI ,  Rajiv DOSHI ,  Kondapavulur T. VENKATESWARA-RAO

IPC分类号： A61N1/36 ,  A61B5/00 ,  A61N1/04 ,  A61B5/30 ,  A61B5/375

摘要： Methods and apparatuses for sensory electrical stimulation of the peripheral nervous system to improve human motor function and performance are described. Methods and devices may be used to enhance physical performance of athletes, professionals, and gamers or improve motor function (hand, finger and limb movement) in patients rehabilitating from neurological deficits and impairments caused by stroke, traumatic brain injury and other neurologic or non-neurologic conditions. These apparatuses and methods may be used for physical training and mental training (to improve memory and functional performance including motor coordination, limb-eye coordination, occupational and recreational skills) through periodic or sustained sensory electrical stimulation. Treatment plans may be based on biomarkers and may be used alone or in combination with other apparatuses. Learning and feedback techniques individualize treatment parameters depending on the subject's neurologic and motor function in diseased patients and healthy users.

公开(公告)号：US20240033516A1

公开(公告)日：2024-02-01

申请号：US18264926

申请日：2022-02-09

申请人： The Regents of the University of California ,  U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS

发明人： Karunesh GANGULY ,  Preeya KHANNA ,  Kyungsoo KIM

IPC分类号： A61N1/36

CPC分类号： A61N1/36103 ,  A61N1/36139 ,  A61N1/36171 ,  A61N1/36178

摘要： Methods and apparatuses for treating a patient having a brain lesion (e.g., a stroke patient) by applying a charge-balanced, low-frequency alternating current stimulation (ACS) to a region of the patient's brain immediately before and/or during a directed movement. The charge-balanced, low-frequency ACS may have a depolarizing phase that is slower than the hyperpolarizing phase (e.g., the depolarizing phase may have a frequency of 15 Hz or less and the hyperpolarizing phase with a frequency greater than 15 Hz). The ACS stimulation field may be greater than 1.5 V/m. The ACS may be applied during a preferred excitation phase.