SYSTEM AND METHOD FOR SPECTROSCOPIC DETERMINATION OF INTENSITY LEVEL AND SIGNAL-TO-NOISE RATIO FROM SAMPLE SCANS

    公开(公告)号:US20240393179A1

    公开(公告)日:2024-11-28

    申请号:US18674335

    申请日:2024-05-24

    Abstract: Methods and systems for predicting signal quality. One analytical instrument support system receives preliminary sample data collected from a short scan of a sample. The analytical instrument support system determines a bright-max intensity level based on preliminary sample data. The analytical instrument support system determines a performance class based on, at least, the bright-max intensity level. The analytical instrument support system determines an intensity-to-time model, the intensity-to-time model includes a plurality of intensity to levels and a plurality of exposure times based on, at least, one or more deviations from an intensity linear model, the one or more deviations associated with the determined performance class. The analytical instrument support apparatus determines a first maximum intensity level based on, at least, a first corresponding exposure time and the intensity-to-time model, or a first parameter exposure time based on, at least, a first corresponding intensity level and the intensity-to-time model.

    SYSTEM AND METHOD FOR SPECTROSCOPIC DETERMINATION OF A CHEMOMETRIC MODEL FROM SAMPLE SCANS

    公开(公告)号:US20250035554A1

    公开(公告)日:2025-01-30

    申请号:US18782763

    申请日:2024-07-24

    Abstract: A computer-implemented method and system are provided. An analytical instrument support system receives a first spectra dataset associated with scans of one or more first samples, the one or more first samples including a target analyte having one or more known levels of a parameter. The analytical instrument support system receives a second spectra dataset associated with scans of one or more second samples. The analytical instrument support system determines one or more spectra arrays by combining (i) the first spectra dataset and (ii) the second spectra dataset. The analytical instrument support system determines a chemometric model for one or more levels of the parameter of the target analyte based on, at least, the one or more spectra arrays and the one or more known levels of the parameter.

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