公开(公告)号：US20070276507A1

公开(公告)日：2007-11-29

申请号：US11706081

申请日：2007-02-12

申请人： Timothy Bertram ,  Andrew Bruce ,  Deepak Jain ,  Manuel Jayo ,  John Ludlow ,  Darrell McCoy ,  Richard Payne ,  Namrata Sangha

发明人： Timothy Bertram ,  Andrew Bruce ,  Deepak Jain ,  Manuel Jayo ,  John Ludlow ,  Darrell McCoy ,  Richard Payne ,  Namrata Sangha

IPC分类号： A61F2/02

CPC分类号： A61F2/02 ,  A61F2/042 ,  A61F2002/047 ,  A61F2002/048 ,  A61L27/3813 ,  A61L27/3826 ,  A61L27/383 ,  A61L27/3882 ,  A61L27/3891 ,  C12N5/0697 ,  C12N2502/1347 ,  C12N2502/253 ,  C12N2533/40

摘要： Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The scaffolds are shaped to conform to at least a part of the organ or tissue structure and may be seeded with one or more cell populations. Inserts, receptacles and ports are also provided for the attachment of tubular vessels to the neo-organ scaffolds. The seeded scaffolds are implanted into the patient at the site in need of treatment to form an organized organ or tissue structure. The scaffolds may be used to form organs or tissues, such as bladders, urethras, valves, and blood vessels.

摘要翻译： 生物相容的合成或天然支架用于需要这种治疗的患者中的器官或组织结构的重建，修复，增加或替换。 支架被成形为符合器官或组织结构的至少一部分，并且可以用一个或多个细胞群体接种。 还提供了插入物，容器和端口用于将管状容器附接到新器官支架。 将种子支架植入需要治疗的部位的患者中以形成有组织的器官或组织结构。 支架可用于形成器官或组织，例如膀胱，尿道，瓣膜和血管。