公开(公告)号：US20190247371A1

公开(公告)日：2019-08-15

申请号：US16335765

申请日：2017-09-21

Applicant: Tsann-Long SU ,  ACADEMIA SINICA

Inventor： Tsann-Long SU ,  Te-Chang LEE

IPC: A61K31/437 ,  A61K45/06 ,  A61P35/00

CPC classification number: A61K31/437 ,  A61K31/4184 ,  A61K31/4745 ,  A61K31/5025 ,  A61K31/5377 ,  A61K31/7048 ,  A61K33/24 ,  A61K45/06 ,  A61P35/00 ,  A61K2300/00

Abstract: A method for treating small cell lung cancer (SCLC). In the method, a therapeutically effective amount of a compound of Formula I: wherein R1, R2 and R3 have the definitions disclosed in the specification is administered alone or in combination with one or more anticancer agents, or surgery, radiation therapy, chemotherapy, and/or targeted therapy.

公开(公告)号：US20200339584A1

公开(公告)日：2020-10-29

申请号：US16764873

申请日：2018-11-16

Applicant: Academia Sinica

Inventor： Te-Chang LEE ,  Tsann-Long SU ,  Tai-Lin CHEN

IPC: C07D487/04 ,  A61P35/02

Abstract: Disclosed herein are novel bifunctional compounds and their uses for the treatment and/or prophylaxis of cancers. The bifunctional compound disclosed herein has the structure of formula (I).