公开(公告)号：US20230285331A1

公开(公告)日：2023-09-14

申请号：US17993027

申请日：2022-11-23

Applicant: UNIVERSITY OF SOUTH CAROLINA

Inventor： SAJISH MATHEW

IPC: A61K31/164 ,  A61K31/198 ,  A61K31/405 ,  A61K31/4164 ,  A61P25/28

CPC classification number: A61K31/164 ,  A61K31/198 ,  A61K31/405 ,  A61K31/4164 ,  A61P25/28

Abstract: Methods and compositions are described herein for modulating protein synthesis, especially monosome translation and DNA damage response, especially short-patch base excision repair (SP-BER), NHEJ and HR for treating a disorder. Compositions include a therapeutically effective amount of a tyrosine or a resveratrol derivative.