公开(公告)号：US3879543A

公开(公告)日：1975-04-22

申请号：US77925168

申请日：1968-11-26

申请人： UPJOHN CO

发明人： KAUGARS GIRTS ,  GEMRICH II EDWIN G

IPC分类号： A01N37/52 ,  C07C243/38 ,  C07F9/22 ,  A01N9/20

CPC分类号： C07C251/72 ,  C07C243/38

摘要： Certain benzoyl chloride phenylhydrazones have been found to be active against insects and mites. The benzoyl ring and the phenylhydrazone ring can be substituted with a halogen atom, a nitro group, or an alkyl group of from 1 to 6 carbon atoms, inclusive. A new class of pentahalobenzoyl chloride phenylhydrazones is described, particularly pentafluorobenzoyl chloride phenylhydrazones. The compounds are prepared by reacting a benzoic acid phenylhydrazide with phosphorus pentachloride to obtain a benzoyl chloride (dichlorophosphinyl) phenylhydrazone that is reacted with phenol to produce the desired benzoyl chloride phenylhydrazones. Certain of the compounds can be prepared by direct chlorination of a benzaldehyde phenylhydrazone. Methods of use and composition are described.

摘要翻译： 已经发现某些苯甲酰氯苯腙对昆虫和螨具有活性。 苯甲酰基环和苯腙环可以被卤素原子，硝基或含1-6个碳原子的烷基取代。 描述了一类新的五卤苯甲酰氯苯腙，特别是五氟苯甲酰氯苯腙。 通过苯甲酸苯肼与五氯化磷反应制得化合物，得到与苯酚反应产生所需苯甲酰氯苯腙的苯甲酰氯（二氯膦氧基）苯腙。 某些化合物可以通过苯甲醛苯腙的直接氯化来制备。 描述使用方法和组成。

公开(公告)号：US3930021A

公开(公告)日：1975-12-30

申请号：US5462070

申请日：1970-07-13

申请人： UPJOHN CO

发明人： KAUGARS GIRTS

IPC分类号： A01N37/52 ,  C07C67/00 ,  C07C241/00 ,  C07C243/38 ,  C07C251/86 ,  A01N9/20

CPC分类号： C07C251/72 ,  C07C243/38

摘要： Certain ( Alpha -fluoroalkyl)benzoyl chloride phenylhydrozones have been found to be anthelmintics and active against arthropod pests. The benzoyl ring and the phenylhydrazone ring can be otherwise substituted with, for example, halogen, nitro, another Alpha -fluoroalkyl group, or an alkyl group.

摘要翻译： 已经发现某些（α-氟代烷基）苯甲酰氯苯基氢化物是驱虫虫，对节肢动物害虫具有活性。 苯甲酰基环和苯腙环可以另外被例如卤素，硝基，另一个α-氟代烷基或烷基取代。

公开(公告)号：US3879542A

公开(公告)日：1975-04-22

申请号：US29788772

申请日：1972-10-16

申请人： UPJOHN CO

发明人： KAUGARS GIRTS

IPC分类号： A01N37/52 ,  A01N9/20

CPC分类号： C07C251/72

摘要： Certain new benzoyl chloride (fluoroalkylphenyl)-hydrazones have been found to be active against arthropod pests and worms. The characterizing fluoroalkyl group on the phenylhydrazone ring can be associated with other substituent atoms and groups. The benzoyl ring can also be substituted. Representative substituent atoms and groups include the halogen atoms, lower-alkyl groups, lower-alkoxy groups, and a nitro group. The fluoroalkyl group is more meaningfully designated an '''' Alpha -Fnalkyl'''' group because fluorine atom substitution on the Alpha -carbon appears to be advantageous. The new compounds can be prepared by reacting a benzoic acid 2( Alpha -Fnalkylphenyl)hydrazide with phosphorus pentachloride to obtain a benzoyl chloride ((dichlorophosphinyl- Alpha Fnalkyl)phenyl)hydrazone that is reacted with phenol to produce the desired benzoyl chloride ( Alpha -Fnalkylphenyl)hydrazones. The compounds having chlorine on the phenylhydrazone ring can be prepared by direct halogenation of benzaldehyde ( Alpha Fnalkylphenyl)hydrazones or a benzoyl chloride ( Alpha Fnalkylphenyl)hydrazone. Methods of anti-arthropodal use and novel formulations adapted for biological use of the new compounds are also described.

摘要翻译： 已经发现某些新的苯甲酰氯（氟烷基苯基） - 腙对节肢动物的害虫和蠕虫有活性。 苯腙环上的表征氟代烷基可以与其它取代基原子和基团相关。 苯甲酰基环也可以被取代。 代表性的取代基原子和基团包括卤素原子，低级烷基，低级烷氧基和硝基。 氟烷基更有意义地被称为“α-烷基”基团，因为在α-碳上的氟原子取代似乎是有利的。

公开(公告)号：US3930020A

公开(公告)日：1975-12-30

申请号：US5462270

申请日：1970-07-13

申请人： UPJOHN CO

发明人： KAUGARS GIRTS

IPC分类号： A01N37/52 ,  C07C251/86 ,  A01N9/20

CPC分类号： A01N37/52

摘要： Certain new ar or ar'' (alkylthio) benzoyl chloride phenylhydrazones have been found to be anthelmintics and active against arthropod pests. The benzoyl ring and the phenylhydrazone ring can be otherwise substituted with, for example, halogen atoms, nitro groups, Alpha -fluoroalkyl groups, other alkylthio groups, and alkyl groups.

摘要翻译： 已发现某些新的ar或ar'（烷硫基）苯甲酰氯苯腙是驱虫虫，对节肢动物害虫有活性。 苯甲酰基环和苯腙环可另外被例如卤素原子，硝基，α-氟代烷基，其它烷硫基和烷基取代。

公开(公告)号：US3551529A

公开(公告)日：1970-12-29

申请号：US3551529D

申请日：1967-11-09

申请人： UPJOHN CO

发明人： KAUGARS GIRTS

IPC分类号： A01N57/12 ,  C07F9/09 ,  C07F9/165 ,  A01N9/36 ,  C07F9/08

CPC分类号： C07F9/097 ,  A01N57/12 ,  C07F9/1657

公开(公告)号：US3870505A

公开(公告)日：1975-03-11

申请号：US32680473

申请日：1973-01-26

申请人： UPJOHN CO

发明人： KAUGARS GIRTS

IPC分类号： A01N37/52 ,  A01N9/20

CPC分类号： C07C251/72

摘要： Certain alkanoyl chloride phenylhydrazones have been found to be active against insects and mites, and also active as herbicides. The phenylhydrazone ring can be substituted. Suitable substituent groups are halogen atoms, the nitro group, the trifluoromethyl group, and alkyl groups of from 1 to 6 carbon atoms, inclusive. The compounds are prepared by reacting an alkanoic acid phenylhydrazide with phosphorus pentachloride to obtain an alkanoyl chloride (dichlorophosphinyl)phenylhydrazone intermediate that is reacted with phenol to produce the desired alkanoyl chloride phenylhydrazone. Certain compounds can be prepared by direct chlorination of an alkanaldehyde phenylhydrazone. Some of the compounds are novel. Methods of use and compositions are described.

摘要翻译： 已经发现某些烷酰氯苯腙对昆虫和螨有活性，并且作为除草剂也是有活性的。 苯腙环可以被取代。 合适的取代基是卤素原子，硝基，三氟甲基和1-6个碳原子的烷基（包括端值）。 通过使链烷酸苯酰肼与五氯化磷反应制得化合物，得到与苯酚反应产生所需的烷酰氯苯腙的烷酰氯（二氯膦氧基）苯腙中间体。 某些化合物可以通过直接氯化烷基苯腙制备。 一些化合物是新的。 描述使用方法和组合物。

公开(公告)号：US3699111A

公开(公告)日：1972-10-17

申请号：US3699111D

申请日：1970-10-05

申请人： UPJOHN CO

发明人： KAUGARS GIRTS

IPC分类号： C07D213/87 ,  C07D333/38 ,  C07D31/40 ,  C07D31/42

CPC分类号： C07D213/87 ,  C07D333/38

摘要： THIS INVENTION RELATES TO NOVEL HETEROCYCLIC ACID CHLORIDE PHENYLHYDRAZONES EMBRACED BY THE FORMULA

(R-CCL=N-NH-),(CL)N-BENZENE

WHEREIN R IS A RADICAL SELECTED FROM THE GROUP CONSISTING OF FURYL, THIENYL AND PYRIDYL, EACH OF WHICH HAS FROM ZERO THROUGH THREE SUBSTUENTS SELECTED FROM THE GROUP CONSISTING OF ALKYL, HALO AND NITRO, AND N IS AN INTEGER OF FROM ZERO THROUGH THREE. THESE COMPOUNDS ARE PRIMARILY USEFUL AS INSECTICIDES AND MITICIDES AND ALSO AS HERBICIDES, ANTIINFLAMMATORIES AND ANTHELMINTICS.