公开(公告)号：US09821028B2

公开(公告)日：2017-11-21

申请号：US14329439

申请日：2014-07-11

申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION

发明人： Mark Eric Cook ,  Daniel Meilahn Schaefer ,  Mitchell Raymond Schaefer ,  Jordan Marshall Sand ,  Larry Smith

IPC分类号： A61K38/20 ,  C07K16/24 ,  A61K39/00

CPC分类号： A61K38/2066 ,  A61K2039/505 ,  C07K16/244 ,  C07K2317/11 ,  C07K2317/23 ,  C07K2317/34

摘要： Disclosed herein are methods of controlling parasitic worms in herbivorous mammals and other species by orally administering an isolated antibody that specifically binds the interleukin-10 peptide or an interleukin-10 peptide. In the case of herbivorous mammals such as cattle, for example, administration of the anti-IL-10 antibodies increases weight gain and increases feed efficiency in the animals.

公开(公告)号：US20160008436A1

公开(公告)日：2016-01-14

申请号：US14329439

申请日：2014-07-11

申请人： Wisconsin Alumni Research Foundation

发明人： Mark Eric Cook ,  Daniel Meilahn Schaefer ,  Mitchell Raymond Schaefer ,  Jordan Marshall Sand ,  Larry Smith

IPC分类号： A61K38/20 ,  C07K16/24

CPC分类号： A61K38/2066 ,  A61K2039/505 ,  C07K16/244 ,  C07K2317/11 ,  C07K2317/23 ,  C07K2317/34

摘要： Disclosed herein are methods of controlling parasitic worms in herbivorous mammals and other species by orally administering an isolated antibody that specifically binds the interleukin-10 peptide or an interleukin-10 peptide. In the case of herbivorous mammals such as cattle, for example, administration of the anti-IL-10 antibodies increases weight gain and increases feed efficiency in the animals.

摘要翻译： 本文公开了通过口服施用特异性结合白细胞介素-10肽或白细胞介素-10肽的分离抗体来控制食草哺乳动物和其他物种中的寄生虫的方法。 在食草哺乳动物例如牛的情况下，例如，施用抗IL-10抗体增加体重增加并提高动物的饲料效率。