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1.发明申请公开(公告)号：US20140127220A1
公开(公告)日：2014-05-08
申请号：US14150354
申请日：2014-01-08
IPC分类号： C07K16/24
CPC分类号： C07K16/244 , A23K20/147 , A23K50/75 , A61K38/00 , A61K38/2066 , A61K39/3955 , A61K2039/505 , C07K14/5428 , C07K16/02 , C07K2317/11 , C07K2317/23 , C07K2317/34
摘要： The present disclosure is directed to interleukin-10 (IL-10) peptides and isolated antibodies that specifically bind to the IL-10 peptides. The IL-10 peptides and the isolated antibodies may be administered alone or as an animal feed additive to treat gastrointestinal protozoan infection in animals.
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公开(公告)号：US10881129B2
公开(公告)日：2021-01-05
申请号：US15673893
申请日：2017-08-10
摘要： A method of making coated avian egg yolk cores includes providing dried avian egg yolk cores having a diameter of 100 to 1500 micrometers, applying avian egg albumen to the dried avian egg yolk cores to provide the coated avian egg yolk cores, and optionally drying the coated avian egg yolk cores, wherein the ratio of dry avian egg albumen to dried avian egg yolk in the coated avian egg yolk cores is 1:10 to 10:1. Also included are the coated avian egg yolk cores, food and feed additives containing the coated avian egg yolk cores and food and feed compositions containing the coated avian egg yolk cores.
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公开(公告)号：US10696734B2
公开(公告)日：2020-06-30
申请号：US15249811
申请日：2016-08-29
IPC分类号： C07K16/00 , C07K16/18 , C07K1/30 , A23K20/147 , A23K50/20 , A23K50/10 , A23K50/75 , A23K50/30 , A23K50/40 , A23K50/80 , A23L33/17 , A61K39/00
摘要： Described herein is secretory IgA isolated from the intestinal luminal fluid and intestinal mucosal of animals such as pigs and cows. Also included are methods of isolating secretory IgA. The secretory IgA is useful in food compositions such as animal and human food compositions as well as pharmaceutical compositions to increase growth rate, improve feed efficiency, reduce gastrointestinal inflammation, reduce a risk of gastrointestinal infection in the animal, or a combination thereof.
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公开(公告)号：US09821029B2
公开(公告)日：2017-11-21
申请号：US14801160
申请日：2015-07-16
申请人： WISCONSIN ALUMNI RESEARCH FOUNDATION , The United States of America as Represented by the Secretary of Agriculture
IPC分类号： A61K38/20 , A23K1/18 , A23K1/17 , C07K16/24 , A61K39/395 , A23K20/147 , A23K20/195 , A23K50/75 , A61K39/00
CPC分类号： A61K38/2066 , A23K20/147 , A23K20/195 , A23K50/75 , A61K39/3955 , A61K2039/505 , A61K2039/542 , A61K2039/545 , C07K16/244 , C07K2317/10 , C07K2317/11
摘要： Described herein are methods of reducing Salmonella in the intestines of poultry in need thereof by administering to a poultry bird an effective amount of an interleukin-10 peptide or an isolated antibody that specifically binds an interleukin-10 peptide. Administering may be performed within 1 to 4 weeks of harvest of the poultry in order to reduce Salmonella transmission to human consumers. Also included herein are finishing feeds that include an interleukin-10 peptide or an isolated antibody that specifically binds an interleukin-10 peptide.
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公开(公告)号：US11692044B2
公开(公告)日：2023-07-04
申请号：US15487619
申请日：2017-04-14
CPC分类号： C07K16/40 , A23K20/147 , A23L33/17 , C07K5/1021 , C12N9/20 , C12Y301/01004 , A23V2002/00 , A61K2039/505 , C07K2317/11 , C07K2317/23 , C07K2317/34 , C07K2317/76
摘要： Described herein are peptides from secretory phospholipase A2-IB and antibodies that can be used to reduce the contribution of the gastrointestinal tract to inflammatory processes including systemic inflammatory responses. Specifically, antibodies that bind specifically a peptide from secretory phospholipase A2-IB prevent death in a mouse model of LPS-induced endotoxemia. The antibodies described herein are particularly useful to treat systemic inflammatory response syndromes, including sepsis.
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公开(公告)号：US11358996B2
公开(公告)日：2022-06-14
申请号：US16711821
申请日：2019-12-12
摘要： Described herein are FGF-23 epitope peptides, methods of producing antibodies in laying hens by injecting the peptides, and methods of improving resistance to eggshell breakage and/or increasing eggshell strength by administering an FGF-23 epitope peptide to a laying hen.
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公开(公告)号：US09821028B2
公开(公告)日：2017-11-21
申请号：US14329439
申请日：2014-07-11
发明人： Mark Eric Cook , Daniel Meilahn Schaefer , Mitchell Raymond Schaefer , Jordan Marshall Sand , Larry Smith
CPC分类号： A61K38/2066 , A61K2039/505 , C07K16/244 , C07K2317/11 , C07K2317/23 , C07K2317/34
摘要： Disclosed herein are methods of controlling parasitic worms in herbivorous mammals and other species by orally administering an isolated antibody that specifically binds the interleukin-10 peptide or an interleukin-10 peptide. In the case of herbivorous mammals such as cattle, for example, administration of the anti-IL-10 antibodies increases weight gain and increases feed efficiency in the animals.
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8.发明申请公开(公告)号：US20160362477A1
公开(公告)日：2016-12-15
申请号：US15249811
申请日：2016-08-29
IPC分类号： C07K16/00 , A23K50/75 , A23L33/17 , A23K20/147
摘要： Described herein is secretory IgA isolated from the intestinal luminal fluid and intestinal mucosal of animals such as pigs and cows. Also included are methods of isolating secretory IgA. The secretory IgA is useful in food compositions such as animal and human food compositions as well as pharmaceutical compositions to increase growth rate, improve feed efficiency, reduce gastrointestinal inflammation, reduce a risk of gastrointestinal infection in the animal, or a combination thereof.
摘要翻译： 本文描述了从动物如猪和牛的肠腔液和肠粘膜分离的分泌型IgA。 还包括分离分泌型IgA的方法。 分泌型IgA可用于食品组合物如动物和人类食物组合物，以及用于增加生长速度，提高饲料效率，减少胃肠道炎症，降低动物胃肠道感染风险的药物组合物或其组合。
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9.发明授权公开(公告)号：US11319367B2
公开(公告)日：2022-05-03
申请号：US16596839
申请日：2019-10-09
发明人： Mark Eric Cook , Jordan Marshall Sand , Sheila Mary McGuirk , Jane Ellen Rieman , Sarah Marie Raabis
摘要： Disclosed herein are methods of reducing a symptom of respiratory disease in a pre-weaned milk-fed mammal by orally administering an isolated antibody that specifically binds the interleukin-10 peptide or an anti-interleukin-10 antibody. Also included are methods of reducing mixing stress in human and non-human mammals by administering an isolated antibody that specifically binds the interleukin-10 peptide or an anti-interleukin-10 antibody. Further included are milk and food compositions including the interleukin-10 peptide or anti-interleukin-10 antibody.
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10.发明授权公开(公告)号：US10017569B2
公开(公告)日：2018-07-10
申请号：US15334542
申请日：2016-10-26
IPC分类号： C07K16/24 , A61K39/395 , A61K38/20 , C07K16/02 , C07K14/54 , A23K20/147 , A23K50/75 , A61K39/00 , A61K38/00
CPC分类号： C07K16/244 , A23K20/147 , A23K50/75 , A61K38/00 , A61K38/2066 , A61K39/3955 , A61K2039/505 , C07K14/5428 , C07K16/02 , C07K2317/11 , C07K2317/23 , C07K2317/34
摘要： The present disclosure is directed to interleukin-10 (IL-10) peptides and isolated antibodies that specifically bind to the IL-10 peptides. The IL-10 peptides and the isolated antibodies may be administered alone or as an animal feed additive to treat gastrointestinal protozoan infection in animals.
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