公开(公告)号：US20200016297A1

公开(公告)日：2020-01-16

申请号：US16585698

申请日：2019-09-27

Applicant: Worcester Polytechnic Institute

Inventor： Marsha Rolle ,  Fioleda Prifti ,  Christopher Malcuit ,  Terri Anne Camesano ,  Tanja Dominko ,  Denis Kole ,  Destin Heilman

IPC: A61L27/54 ,  C07K14/78 ,  C07K14/47 ,  C12N15/62

Abstract: The invention provides a scaffold of extracellular matrix polymers with recombinant chimeric peptides tethered thereto. The invention also provides recombinant chimeric peptides of antimicrobial peptides and extracellular matrix binding domains. The invention also provides methods for treating chronic wounds using the scaffold and/or recombinant chimeric peptides.