公开(公告)号：US11670398B2

公开(公告)日：2023-06-06

申请号：US16613507

申请日：2018-05-18

申请人： Yamaguchi University ,  Toyo Kohan Co., Ltd.

发明人： Hideyasu Matsuyama ,  Yoshihiko Hamamoto ,  Yusuke Fujita ,  Yoshiaki Yamamoto ,  Ryouichi Tsunedomi ,  Mitsuyoshi Oba ,  Hirofumi Yamano ,  Yukiha Ishikawa

IPC分类号： G16B20/20 ,  G01N33/53 ,  G16C20/30

CPC分类号： G16B20/20 ,  G01N33/53 ,  G16C20/30

摘要： It is intended to conveniently determine the pharmacokinetics of axitinib and to predict the therapeutic effect of axitinib. The present invention provides a method for determining the pharmacokinetics of axitinib, comprising the step of calculating a predicted pharmacokinetic parameter of axitinib using specific gene polymorphisms and background factors regarding a test subject.

公开(公告)号：US20210158893A1

公开(公告)日：2021-05-27

申请号：US16613507

申请日：2018-05-18

申请人： Yamaguchi University ,  Toyo Kohan Co., Ltd.

发明人： Hideyasu Matsuyama ,  Yoshihiko Hamamoto ,  Yusuke Fujita ,  Yoshiaki Yamamoto ,  Ryouichi Tsunedomi ,  Mitsuyoshi Oba ,  Hirofumi Yamano ,  Yukiha Ishikawa

IPC分类号： G16B20/20 ,  G16C20/30

摘要： It is intended to conveniently determine the pharmacokinetics of axitinib and to predict the therapeutic effect of axitinib. The present invention provides a method for determining the pharmacokinetics of axitinib, comprising the step of calculating a predicted pharmacokinetic parameter of axitinib using specific gene polymorphisms and background factors regarding a test subject.