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公开(公告)号：US20100028868A1
公开(公告)日：2010-02-04
申请号：US12181928
申请日：2008-07-29
申请人： Yuchi Hwang , Kuang-Den Chen , Chingwei Chang , Jui-Lin Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
发明人： Yuchi Hwang , Kuang-Den Chen , Chingwei Chang , Jui-Lin Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/172
摘要： Sets of nucleic acids and methods for predicting a subject's responsiveness to therapy for liver disorders.
摘要翻译： 用于预测受试者对肝脏疾病治疗反应的核酸和方法。
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公开(公告)号：US07405043B2
公开(公告)日：2008-07-29
申请号：US10880315
申请日：2004-06-29
申请人： Yuchi Hwang , Kuang-Den Chen , Chingwei Chang , Jui-Lin Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
发明人： Yuchi Hwang , Kuang-Den Chen , Chingwei Chang , Jui-Lin Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/172
摘要： Sets of nucleic acids and methods for predicting a subject's responsiveness to therapy for liver disorders.
摘要翻译： 用于预测受试者对肝脏疾病治疗反应的核酸和方法。
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公开(公告)号：US20050288497A1
公开(公告)日：2005-12-29
申请号：US10880315
申请日：2004-06-29
申请人： Yuchi Hwang , Kuang-Den Chen , Chingwei Chang , Jui-Lin Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
发明人： Yuchi Hwang , Kuang-Den Chen , Chingwei Chang , Jui-Lin Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/156 , C12Q2600/172
摘要： Sets of nucleic acids and methods for predicting a subject's responsiveness to therapy for liver disorders.
摘要翻译： 用于预测受试者对肝脏疾病治疗反应的核酸和方法。
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4.发明授权Method for detecting a propensity of an individual to respond effectively to treatment of interferon-α and ribavirin combined therapy 有权用于检测个体倾向以有效响应治疗干扰素-α和利巴韦林联合治疗的方法公开(公告)号：US07108978B2
公开(公告)日：2006-09-19
申请号：US10618620
申请日：2003-07-15
申请人： Jui-Lin Chen , Yuchi Hwang , Min-Pey Ding , Wen-Pi Chu , Shu-Ching Wang , Kuei-Ling Belinda Chen , Wan-Lin Yao , Kuang-Den Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
发明人： Jui-Lin Chen , Yuchi Hwang , Min-Pey Ding , Wen-Pi Chu , Shu-Ching Wang , Kuei-Ling Belinda Chen , Wan-Lin Yao , Kuang-Den Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
CPC分类号： C12Q1/6883 , C12Q2600/156
摘要： It is provided isolated polynucleotides that include sequences from genomic region around the gene CD 81. The polynucleotides include polymorphisms associated with treatment response of HCV patients to interferon-α and ribavirin combined therapy and are useful as the probes in screening for patients who will response to interferon-α and ribavirin combined therapy. It is further provided linkage disequilibrium structure of the CD81 gene and haplotype information within a particular LD block, which can be used for prediction of the treatment outcome of the interferon-α and ribavirin combined therapy on HCV patients.
摘要翻译： 提供了分离的多核苷酸，其包括来自基因CD81周围的基因组区域的序列。多核苷酸包括与HCV患者对干扰素-α和利巴韦林联合治疗的治疗反应相关的多态性，并且可用作筛选将响应于 干扰素-α和利巴韦林组合治疗。 进一步提供CD81基因的连锁不平衡结构和特定LD区段内的单倍型信息，可用于预测干扰素-α和利巴韦林联合治疗对HCV患者的治疗结果。
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5.发明申请公开(公告)号：US20050014159A1
公开(公告)日：2005-01-20
申请号：US10618620
申请日：2003-07-15
申请人： Jui-Lin Chen , Yuchi Hwang , Min-Pey Ding , Wen-Pi Chu , Shu-Ching Wang , Kuei-Ling Chen , Wan-Lin Yao , Kuang-Den Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
发明人： Jui-Lin Chen , Yuchi Hwang , Min-Pey Ding , Wen-Pi Chu , Shu-Ching Wang , Kuei-Ling Chen , Wan-Lin Yao , Kuang-Den Chen , Ding-Shinn Chen , Pei-Jer Chen , Ming-Yang Lai
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/156
摘要： It is provided isolated polynucleotides that include sequences from genomic region around the gene CD 81. The polynucleotides include polymorphisms associated with treatment response of HCV patients to interferon-α and ribavirin combined therapy and are useful as the probes in screening for patients who will response to interferon-α and ribavirin combined therapy. It is further provided linkage disequilibrium structure of the CD81 gene and haplotype information within a particular LD block, which can be used for prediction of the treatment outcome of the interferon-α and ribavirin combined therapy on HCV patients.
摘要翻译： 提供了分离的多核苷酸，其包括来自基因CD81周围的基因组区域的序列。多核苷酸包括与HCV患者对干扰素-α和利巴韦林联合治疗的治疗反应相关的多态性，并且可用作筛选将响应于 干扰素-α和利巴韦林组合治疗。 进一步提供CD81基因的连锁不平衡结构和特定LD区段内的单倍型信息，可用于预测干扰素-α和利巴韦林联合治疗对HCV患者的治疗结果。
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6.发明申请FUROST-5-ENE-3, 22, 26-TRIOL GLYCOSIDE COMPOUND FOR PREVENTING AND TREATMENT CANCER 审中-公开用于预防和治疗癌症的FUROST-5-ENE-3,22,26-三聚氰尿酸化合物公开(公告)号：US20100179098A1
公开(公告)日：2010-07-15
申请号：US12440273
申请日：2006-09-07
IPC分类号： A61K31/7048 , A61P35/00
CPC分类号： A61K31/7048
摘要： A pharmaceutical composition for preventing and treating cancer comprising furost-5-ene-3,22,26-triol glycoside, which can be used to prevent and treat cancer by promoting apoptosis.
摘要翻译： 一种用于预防和治疗癌症的药物组合物，其包含呋喃葡萄糖-5-烯-3,22,26-三醇糖苷，其可用于通过促进细胞凋亡来预防和治疗癌症。
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