专利检索 ap:("ZEALAND PHARMA A/S" OR "BOSTON MEDICAL CENTER CORPORATION") AND inv:"Dongjoon Kim" 第 1 页

1.

发明授权
Gap junction intercellular communication modulators and their use for the treatment of diabetic eye disease 有权

公开(公告)号：US11324799B2

公开(公告)日：2022-05-10

申请号：US16609963

申请日：2018-05-04

申请人： ZEALAND PHARMA A/S , BOSTON MEDICAL CENTER CORPORATION

发明人： Bjarne Due Larsen , Ulrik Mouritzen , Dongjoon Kim , Sayon Roy

IPC分类号： A61K38/08 , A61P3/10 , A61K31/40

摘要： The use of gap junction intercellular communication (GJIC) modulators in the treatment or prevention of diabetic eye disease is disclosed, and more particularly to their use for the treatment or prevention of early stage diabetic retinopathy and diabetic macular edema by inhibiting apoptosis of retinal endothelial cells and inhibiting pericyte loss.