公开(公告)号：US4042627A

公开(公告)日：1977-08-16

申请号：US618244

申请日：1975-09-30

申请人： Gregoire Kalopissis ,  Andree Bugaut ,  Francoise Estradier

发明人： Gregoire Kalopissis ,  Andree Bugaut ,  Francoise Estradier

IPC分类号： A61K8/41 ,  A61Q5/10 ,  C07C275/40 ,  C09B53/02 ,  C07C91/42

CPC分类号： A61Q5/10 ,  A61K8/413 ,  C07C275/40 ,  C09B53/02

摘要： Diphenylamines of the formula ##STR1## wherein R.sub.1 and R.sub.2 each independently represent hydrogen, halogen or lower alkyl containing 1-4 carbon atoms with at least one of R.sub.1 and R.sub.2 being other than hydrogen; R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 each independently represent hydrogen or lower alkyl optionally substituted with hydroxy, carbamyl, piperidinyl or acylamino; R.sub.3 and R.sub.6 or R.sub.4 and R.sub.7 also optionally forming together with the carbon and nitrogen atoms to which they are attached, a dihydrooxazine or pyrroline heterocycle; and Z represents amino, acylamino or hydroxy; and the acid salts of said diphenylamines. These diphenylamines are usefully employed in cosmetic compositions for the hair including hair dye compositions and hair setting lotion compositions.

摘要翻译： 其中R 1和R 2各自独立地表示氢，卤素或含有1-4个碳原子的低级烷基，其中R 1和R 2中的至少一个不是氢; R3，R4，R5，R6和R7各自独立地表示氢或任选被羟基，氨基甲酰基，哌啶基或酰基氨基取代的低级烷基; R 3和R 6或R 4和R 7还任选地与它们所连接的碳原子和氮原子一起形成，二氢恶嗪或吡咯啉杂环; Z表示氨基，酰氨基或羟基; 和所述二苯胺的酸式盐。 这些二苯胺可用于头发的化妆品组合物中，包括染发组合物和头发定型洗剂组合物。

公开(公告)号：US4008999A

公开(公告)日：1977-02-22

申请号：US551653

申请日：1975-02-21

申请人： Gregoire Kalopissis ,  Andree Bugaut ,  Francoise Estradier

发明人： Gregoire Kalopissis ,  Andree Bugaut ,  Francoise Estradier

IPC分类号： A61K8/41 ,  A61Q5/10 ,  C07C275/40 ,  A61K7/13

CPC分类号： A61K8/415 ,  A61K8/413 ,  A61Q5/10 ,  C07C275/40

摘要： Diphenylamine of the formula ##STR1## wherein R.sub.1 and R.sub.4 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl having 1-6 carbon atoms, lower alkoxy having 1-6 carbon atoms, amino, lower alkyl amino wherein the alkyl moiety has 1-6 carbon atoms, acylamino, lower carbamylalkyl amino wherein the alkyl moiety has 1-6 carbon atoms, lower hydroxylalkyl amino wherein the alkyl moiety has 1-6 carbon atoms, lower carbalkoxy amino wherein the alkoxy moiety has 1-6 carbon atoms and ureido;R.sub.2 and R.sub.3 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl having 1-6 carbon atoms, lower alkoxy having 1-6 carbon atoms, acylamino and ureido;R.sub.5 and R.sub.8 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl having 1-6 carbon atoms and lower alkoxy having 1-6 carbon atoms; andR.sub.6 and R.sub.7 are lower alkyl having 1-6 carbon atoms, with the proviso that (a) when both R.sub.6 and R.sub.7 represent methyl (1) one of R.sub.1 and R.sub.4 must represent a member selected from the group consisting of amino, lower alkyl amino wherein the alkyl moiety has 1-6 carbon atoms, lower carbamylalkyl amino wherein the alkyl moiety has 1-6 carbon atoms, lower hydroxyalkyl amino wherein the alkyl moiety has 1-6 carbon atoms and ureido, or (2) one of R.sub.1 and R.sub.4 represent acylamino and R.sub.2 and R.sub.3 are not both hydrogen, and (b) that when both R.sub.6 and R.sub.7 represent ethyl, R.sub.2 and R.sub.3 are other than tertiobutyl.The said diphenylamine is employed in a dye composition for dyeing keratinic fibers.

摘要翻译： 式IMA的二苯胺其中R 1和R 4各自独立地表示选自氢，卤素，具有1-6个碳原子的低级烷基，具有1-6个碳原子的低级烷氧基，氨基，低级烷基氨基， 烷基部分具有1-6个碳原子，酰基氨基，低级氨基甲酰基烷基氨基，其中烷基部分具有1-6个碳原子，低级羟基烷基氨基，其中烷基部分具有1-6个碳原子，低级烷氧基氨基，其中烷氧基部分具有1- 6个碳原子和脲基; R2和R3各自独立地表示选自氢，卤素，具有1-6个碳原子的低级烷基，具有1-6个碳原子的低级烷氧基，酰氨基和脲基的成员; R5和R8各自独立地表示选自氢，卤素，具有1-6个碳原子的低级烷基和具有1-6个碳原子的低级烷氧基的成员; 并且R 6和R 7为具有1-6个碳原子的低级烷基，条件是（a）当R 6和R 7均表示甲基时，R 1和R 4中的一个必须表示选自氨基，低级烷基 氨基，其中烷基部分具有1-6个碳原子，其中烷基部分具有1-6个碳原子的低级氨基甲酰基烷基氨基，其中烷基部分具有1-6个碳原子的低级羟烷基氨基和脲基，或（2）R1和 R4代表酰基氨基，R2和R3不同时为氢，（b）当R6和R7都表示乙基时，R2和R3不是叔丁基。

公开(公告)号：US3972937A

公开(公告)日：1976-08-03

申请号：US499189

申请日：1974-08-21

申请人： Gregoire Kalopissis ,  Andree Bugaut ,  Francoise Estradier

发明人： Gregoire Kalopissis ,  Andree Bugaut ,  Francoise Estradier

IPC分类号： A61K8/41 ,  A61Q5/10 ,  C07C275/40 ,  C09B53/02 ,  C07C91/42

CPC分类号： C07C275/40 ,  A61K8/413 ,  A61Q5/10 ,  C09B53/02

摘要： Hair dye and hair-setting lotion compositions contain a diphenylamine of the formula ##SPC1##Wherein Z represents amino, acylamino or hydroxy, R.sub.1, R.sub.2 and R.sub.3 represent hydrogen or lower alkyl, R.sub.4 represents hydrogen, lower alkyl or together with R.sub.1 and the nitrogen atom to which R.sub.4 is attached form a dihydro-oxazine or pyrroline heterocycle and R.sub.5 represents hydrogen, lower alkyl or together with R.sub.2 and the nitrogen atom to which R.sub.5 is attached form a dihydro-oxazine or pyrroline heterocycle and the acid salts of said diphenylamine.

摘要翻译： 染发剂和护发组合物含有下式的二苯胺：其中Z表示氨基，酰氨基或羟基，R1，R2和R3表示氢或低级烷基，R4表示氢，低级烷基或与R1及氮原子一起 R4连接形成二氢恶嗪或吡咯啉杂环，R 5表示氢，低级烷基或与R 2连接，与R 5连接的氮原子形成二氢恶嗪或吡咯啉杂环，以及所述二苯胺的酸式盐。