公开(公告)号：US07803166B2

公开(公告)日：2010-09-28

申请号：US11696221

申请日：2007-04-04

申请人： Michael J. Stokes ,  Mark S. Zeiner

发明人： Michael J. Stokes ,  Mark S. Zeiner

IPC分类号： A61B17/10

CPC分类号： A61B17/1285 ,  A61B17/1227 ,  A61B2017/306

摘要： A method for creating a plication within a hollow organ. The method uses an elongated member having an end effector at its distal end. The end effector has an outer cylinder having at least one opening in its cylindrical wall, and an inner cylinder having at least one opening in its cylindrical wall. The inner cylinder is at least partially disposed within the outer cylinder such that the apertures can at least partially overlap. The cylinders are rotatable with respect to each other. The method includes the step of inserting the end effector within an organ of a patient such that it is in contact with tissue. The method also involves applying vacuum through the elongated member so as to dispose tissue within the inner cylinder. The method also involves creating a plication by rotating the cylinders with respect to each other.

摘要翻译： 一种在中空器官内形成脓肿的方法。 该方法使用在其远端具有端部执行器的细长构件。 末端执行器具有在其圆柱形壁中具有至少一个开口的外圆柱体，以及在其圆柱形壁中具有至少一个开口的内圆柱体。 内筒至少部分地设置在外筒内，使得孔可以至少部分重叠。 气缸可相对于彼此旋转。 该方法包括将末端执行器插入患者的器官以使其与组织接触的步骤。 该方法还涉及通过细长构件施加真空以将组织置于内筒内。 该方法还涉及通过相对于彼此旋转气缸而产生褶皱。

公开(公告)号：US07686831B2

公开(公告)日：2010-03-30

申请号：US11394168

申请日：2006-03-31

申请人： Michael J. Stokes ,  Mark S. Zeiner ,  Jeffrey S. Swayze ,  Mark S. Ortiz ,  Frederick E. Shelton, IV

发明人： Michael J. Stokes ,  Mark S. Zeiner ,  Jeffrey S. Swayze ,  Mark S. Ortiz ,  Frederick E. Shelton, IV

IPC分类号： A61B17/04

CPC分类号： A61B17/0469 ,  A61B17/1114 ,  A61B2017/00407 ,  A61B2017/0053 ,  A61B2017/0608 ,  A61B2017/306 ,  A61F5/0086

摘要： A method of securing a suture includes the steps of inserting the suture through a passageway into a body of a patient, inserting the suture into and back out of tissue, tying a knot along a length of the suture, and fusing the knot.

摘要翻译： 固定缝合线的方法包括以下步骤：将缝合线穿过通道插入患者体内，将缝合线插入和退出组织，沿着缝合线的长度捆扎结，并将结融合。

公开(公告)号：US20080249561A1

公开(公告)日：2008-10-09

申请号：US11696231

申请日：2007-04-04

申请人： Michael J. Stokes ,  Mark S. Zeiner

发明人： Michael J. Stokes ,  Mark S. Zeiner

IPC分类号： A61B17/03

CPC分类号： A61B17/1227 ,  A61B17/1285 ,  A61B2017/306

摘要： A method for creating a plication within a hollow organ. The method uses an elongated member having an end effector attached to its distal end. The end effector has a substantially hollow housing, a fixed jaw extending distally from the housing, and a retractable jaw located within the housing. The method involves the step of inserting the end effector within an organ of a patient such that it is in contact with tissue. The method also involves applying vacuum through the elongated member so as to dispose tissue on the fixed jaw and at least partially within the housing. The method also involves creating a plication by sliding the retractable jaw so that it juxtaposes the fixed jaw.

摘要翻译： 一种在中空器官内形成脓肿的方法。 该方法使用具有附接到其远端的末端执行器的细长构件。 末端执行器具有基本上中空的壳体，从壳体向远侧延伸的固定夹爪以及位于壳体内的可伸缩爪。 该方法包括将末端执行器插入患者的器官以使其与组织接触的步骤。 该方法还涉及通过细长构件施加真空，以便将组织布置在固定夹爪上并且至少部分地在壳体内。 该方法还涉及通过滑动可伸缩钳口使其并置固定夹爪来产生折痕。

公开(公告)号：US08602286B2

公开(公告)日：2013-12-10

申请号：US12690285

申请日：2010-01-20

申请人： Lawrence Crainich ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

发明人： Lawrence Crainich ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

IPC分类号： A61B17/068

CPC分类号： A61B17/0682 ,  A61B17/068 ,  A61B17/1285 ,  A61B2017/0645

摘要： A mechanism for feeding a fastener including a housing having a longitudinal axis and at least one fastener within the housing. The fastener has a crown and at least two legs extending therefrom. The fastener is disposed within the housing in a first plane parallel to the longitudinal axis. The mechanism includes an elongated actuator disposed within the housing. The actuator has a shaft substantially parallel to the longitudinal axis of the mechanism and rigidly spaced from the fastener in a second plane. The actuator has at least one radially extending advancer disposed along a length thereof, and a mechanism for rotating the actuator so that the advancer engages the fastener.

摘要翻译： 一种用于馈送紧固件的机构，所述紧固件包括具有纵向轴线的壳体和在所述壳体内的至少一个紧固件。 紧固件具有冠部并且从其延伸的至少两个腿部。 紧固件在平行于纵向轴线的第一平面内设置在壳体内。 该机构包括设置在壳体内的细长致动器。 致动器具有基本上平行于机构的纵向轴线的轴并且在第二平面中与紧固件刚性地间隔开。 致动器具有至少一个沿其长度布置的径向延伸的推进器，以及用于使致动器旋转的机构，使得推进器接合紧固件。

公开(公告)号：US08585628B2

公开(公告)日：2013-11-19

申请号：US13105006

申请日：2011-05-11

申请人： Jason L. Harris ,  Mark S. Ortiz ,  Mark D. Overmyer ,  Michael J. Stokes

发明人： Jason L. Harris ,  Mark S. Ortiz ,  Mark D. Overmyer ,  Michael J. Stokes

IPC分类号： A61B19/00

CPC分类号： A61F5/0076 ,  A61B2017/0404 ,  A61F5/0083

摘要： Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance.

摘要翻译： 方法和装置调节胃内生长素释放激素的激活，以治疗体重紊乱，促进学习和记忆功能，治疗压力诱导的抑郁症和控制睡眠持续时间。 在一个实施方案中，用于调节胃内生长素释放激素激活的方法包括从胃中的食物含量和膳食脂质中分离未活化的生长素释放肽激素的方法。 这些用于隔离的装置可以采取任何数量的形式，并且可以包括外科手术，植入装置或可摄取物质中的一种或多种。

公开(公告)号：US20100187285A1

公开(公告)日：2010-07-29

申请号：US12359354

申请日：2009-01-26

申请人： Jason L. Harris ,  Lawrence Craininch ,  Michael J. Stokes

发明人： Jason L. Harris ,  Lawrence Craininch ,  Michael J. Stokes

IPC分类号： A61B17/115 ,  A61B17/064

CPC分类号： A61B17/064 ,  A61B17/00234 ,  A61B17/0684 ,  A61B17/29 ,  A61B2017/00818 ,  A61B2017/07264

摘要： A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains a plurality of surgical fasteners. The surgical fasteners have a base, and two legs extending away from the base, wherein the legs have distal end segments. The fastener has a first shape wherein the distal end segments bend towards each other so that they are adjacent and form the fastener into a first loop. The fastener has a second shape wherein the distal end segments are spaced apart from each other along substantially an entire length thereof. The fastener also has a third shape wherein the distal end segments bend towards each other in so that they are adjacent and form the fastener into a second loop wherein the second loop having a width greater than a width of the first loop. The applier includes a means for forming the fastener into the second and third shapes.

摘要翻译： 具有手柄和从手柄延伸的紧固件外壳的手术紧固件施加器。 外壳包含多个手术紧固件。 手术紧固件具有基部和两个远离基部延伸的腿，其中腿具有远端段。 紧固件具有第一形状，其中远端段彼此弯曲，使得它们相邻并且将紧固件形成第一回路。 紧固件具有第二形状，其中远端段在其大致整个长度上彼此间隔开。 紧固件还具有第三形状，其中远端段彼此弯曲成使得它们相邻并且将紧固件形成第二环，其中第二环具有大于第一环的宽度的宽度。 施加器包括用于将紧固件形成第二和第三形状的装置。

公开(公告)号：US20120193394A1

公开(公告)日：2012-08-02

申请号：US13164949

申请日：2011-06-21

申请人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Jeffrey C. Cerier ,  Jonathan B. O'Keefe ,  Keith D. Boudreau

发明人： Matthew D. Holcomb ,  Jason L. Harris ,  Michael J. Stokes ,  Jeffrey C. Cerier ,  Jonathan B. O'Keefe ,  Keith D. Boudreau

IPC分类号： A61B17/068

CPC分类号： A61B17/0644 ,  A61B17/0682 ,  A61B2017/00818

摘要： A fastener applying device for surgically attaching tissue together. The device includes a staple housing having a proximal end attached to a handle, a distal end and a longitudinal axis therebetween. There is at least one fastener within the housing. The device includes an anvil movable within the staple housing. The anvil has a proximal position and a distal position, wherein when in the distal position a distal end of the anvil extends distal to the distal end of the staple housing by a distance. The device further includes an adjustment nut connecting the staple housing to the handle, wherein rotation of the adjustment nut changes the distance.

摘要翻译： 一种用于将组织手术附接在一起的紧固件施加装置。 该装置包括具有附接到手柄的近端的钉仓，其间的远端和纵向轴线。 壳体内至少有一个紧固件。 该装置包括可在钉仓内移动的砧座。 砧座具有近端位置和远端位置，其中当远端位置时，砧座的远端远离钉钉仓的远端延伸一定距离。 该装置还包括将钉仓与手柄连接的调节螺母，其中调节螺母的旋转改变距离。

公开(公告)号：US20110295286A1

公开(公告)日：2011-12-01

申请号：US13105006

申请日：2011-05-11

申请人： Jason L. Harris ,  Mark S. Ortiz ,  Mark D. Overmyer ,  Michael J. Stokes

发明人： Jason L. Harris ,  Mark S. Ortiz ,  Mark D. Overmyer ,  Michael J. Stokes

IPC分类号： A61B17/11

CPC分类号： A61F5/0076 ,  A61B2017/0404 ,  A61F5/0083

摘要： Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance.

摘要翻译： 方法和装置调节胃内生长素释放激素的激活，以治疗体重紊乱，促进学习和记忆功能，治疗压力诱导的抑郁症和控制睡眠持续时间。 在一个实施方案中，用于调节胃内生长素释放激素激活的方法包括从胃中的食物含量和膳食脂质中分离未活化的生长素释放肽激素的方法。 这些用于隔离的装置可以采取任何数量的形式，并且可以包括外科手术，植入装置或可摄取物质中的一种或多种。

公开(公告)号：US20110295179A1

公开(公告)日：2011-12-01

申请号：US13105014

申请日：2011-05-11

申请人： Jason L. Harris ,  Mark S. Ortiz ,  Mark D. Overmyer ,  Michael J. Stokes

发明人： Jason L. Harris ,  Mark S. Ortiz ,  Mark D. Overmyer ,  Michael J. Stokes

IPC分类号： A61M5/00

CPC分类号： A61F5/0083 ,  A61F5/0076

摘要： Methods and devices regulate the activation of ghrelin hormones within a stomach in order to treat weight disorders, to promote learning and memory functions, to treat stress-induced depression, and to control sleep duration. In one embodiment, a method for regulating activation of ghrelin hormones within a stomach comprises a means for isolating non-activated ghrelin hormones from food content and dietary lipids within the stomach. These means for isolating may take any number of forms and may comprise one or more of a surgical procedure, an implanted device, or an ingestible substance.

公开(公告)号：US20100187284A1

公开(公告)日：2010-07-29

申请号：US12690285

申请日：2010-01-20

申请人： Lawrence Crainich ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

发明人： Lawrence Crainich ,  Jason L. Harris ,  Michael J. Stokes ,  Matthew D. Holcomb ,  Jonathan B. O'Keefe ,  Keith D. Boudreau ,  Jeffrey C. Cerier

IPC分类号： A61B17/068

CPC分类号： A61B17/0682 ,  A61B17/068 ,  A61B17/1285 ,  A61B2017/0645

摘要： A mechanism for feeding a fastener including a housing having a longitudinal axis and at least one fastener within the housing. The fastener has a crown and at least two legs extending therefrom. The fastener is disposed within the housing in a first plane parallel to the longitudinal axis. The mechanism includes an elongated actuator disposed within the housing. The actuator has a shaft substantially parallel to the longitudinal axis of the mechanism and rigidly spaced from the fastener in a second plane. The actuator has at least one radially extending advancer disposed along a length thereof, and a mechanism for rotating the actuator so that the advancer engages the fastener.

摘要翻译： 一种用于馈送紧固件的机构，所述紧固件包括具有纵向轴线的壳体和在所述壳体内的至少一个紧固件。 紧固件具有冠部并且从其延伸的至少两个腿部。 紧固件在平行于纵向轴线的第一平面内设置在壳体内。 该机构包括设置在壳体内的细长致动器。 致动器具有基本上平行于机构的纵向轴线的轴并且在第二平面中与紧固件刚性地间隔开。 致动器具有至少一个沿其长度布置的径向延伸的推进器，以及用于使致动器旋转的机构，使得推进器接合紧固件。